Results 51 to 60 of about 979,842 (317)

Decision-analytic modeling for early health technology assessment of medical devices – a scoping review

GMS German Medical Science, 2022
Objective: The goal of this review was to identify decision-analytic modeling studies in early health technology assessments (HTA) of high-risk medical devices, published over the last three years, and to provide a systematic overview of model purposes ...
Conrads-Frank, Annette, Schnell-Inderst, Petra, Neusser, Silke, Hallsson, Lára R., Stojkov, Igor, Siebert, Silke, Kühne, Felicitas, Jahn, Beate, Siebert, Uwe, Sroczynski, Gabi   +9 more
doaj   +1 more source

Identifying priority technical and context-specific issues in improving the conduct, reporting and use of health economic evaluation in low- and middle-income countries

Health Research Policy and Systems, 2018
Background The use of economic evaluation in healthcare policies and decision-making, which is limited in low- and middle-income countries (LMICs), might be promoted through the improvement of the conduct and reporting of studies. Although the literature
Alia Luz, Benjarin Santatiwongchai, Juntana Pattanaphesaj, Yot Teerawattananon   +3 more
doaj   +1 more source

Mapping the characteristics, concepts and methodologies of matching-adjusted indirect comparison studies assessing pharmacological therapies in oncology: a scoping review protocol

BMJ Open, 2023
Introduction Matching-adjusted indirect comparison (MAIC) studies are a subtype of indirect comparison, which uses propensity score weighting to enhance comparability.
Haliton Alves De Oliveira Junior, Cecília Menezes Farinasso, Aline Pereira Rocha, Flávia Cordeiro Medeiros, Lays Pires Marra, Patrícia Carmo Silva Parreira, Layssa Andrade Oliveira, Vinícius Lins Ferreira, Rosa Camila Lucchetta   +8 more
doaj   +1 more source

Introduction to Health Technology Assessment

Journal of Cardiovascular Echography, 2012
Abstract The objective of this review is to introduce the readers of this journal to the knowledge of some basic aspects of Health Technology Assessment (HTA). HTA starts from the need of the “political governance” to provide adequate health services to the citizens’ demand without overloading the budgets and with a correct resource management.
Di Bello, Vitantonio, Tonti, Gianni, Barletta, Giuseppe, Di Salvo, Giovanni, Mancino, Massimo, LA CARRUBBA, SALVATORE, Canterin, Francesco A., CARERJ, Scipione, La Canna, Giovanni   +8 more
openaire   +3 more sources

Surrogate Endpoints in Health Technology Assessment [PDF]

, 2020
In the drive towards faster patient access to treatments, health technology assessment (HTA) agencies are increasingly faced with reliance on evidence from surrogate endpoints, leading to increased decision uncertainty.
Antal Zemplenyi, Rabbe, S, Möllenkamp, M, Federici, C. (Carlo), Florian Dams, Kosta Shatrov, Meilin Möllenkamp, Dams, F, Ciani, O. (Oriana), Taylor, R, Grigore, Bogdan,, Grigore, B. (Bogdan), Shatrov, Kosta, Rabbe, Stefan, Zemplenyi, Antal, Federici, C, Rod S. Taylor, Shatrov, K, Zemplenyi, A. (Antal), Möllenkamp, Meilin, Grigore, Bogdan, Möllenkamp, M. (Meilin), Grigore, B, Dams, Florian, Ciani, O, Ciani, Oriana,, Stefan Rabbe, Groot, S. (Saskia) de, Ciani, Oriana, Taylor, Rod S., Shatrov, K. (Kosta), Dams, F. (Florian), Taylor, R.S. (Rod), Zemplenyi, A, Oriana Ciani, Saskia de Groot, de Groot, Saskia, Bogdan Grigore, Carlo Federici, Taylor, Rod S, Rabbe, S. (Stefan), Federici, Carlo   +41 more
core   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

The use of various genetically engineered biological drugs and selective immunosuppressants within the current provider-payment model of russian diagnosis-related groups

Фармакоэкономика, 2020
Diagnosis-Related Groups (DRG) for the payment for biological therapy were created at the stage of the pilot project and their coefficients of input intensity were not revised since then.
E. V. Derkach, E. A. Pyadushkina, M. V. Avxentyeva, T. V. Boyarskaya, E. E. Yagnenkova, A. S. Mokrova, M. M. Maryanyan   +6 more
doaj   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Ablative therapy for people with localised prostate cancer: a systematic review and economic evaluation [PDF]

, 2015
BACKGROUND: For people with localised prostate cancer, active treatments are effective but have significant side effects. Minimally invasive treatments that destroy (or ablate) either the entire gland or the part of the prostate with cancer may be as ...
Gray, J, Pickard, R, Brazzelli, M, Rushton, SP, Shirley, MD, N'Dow, J, Adewuyi, TE, Vale, L, Robertson, C, MacLennan, G, Lam, TB, Jayakody, S, Rothnie, K, Ramsay, CR, Hislop, J, MacLennan, S, Fraser, C   +16 more
core   +1 more source

High-cost users still came to hospitals during the COVID-19 pandemic during first wave data in Thailand: secondary data analysis

BMC Public Health
Background The phenomenon of high-cost users (HCUs) in health care occurs when a small proportion of patients account for a large proportion of health care expenditures.
Picharee Karunayawong, Piyada Gaewkhiew, Myka Harun Sarajan, Chulathip Boonma, Rukmanee Butchon, Jarawee Sukmanee, Thanayut Saeraneesopon, Yot Teerawattananon, Wanrudee Isaranuwatchai   +8 more
doaj   +1 more source