Results 51 to 60 of about 23,885,267 (262)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
At the request of the Department of Health, HIQA undertook a descriptive analysis of epidemiological indicators in order to describe the burden of COVID-19 as it has occurred across a range of European countries from 1 January 2020 up to 30 November ...
Health Information and Quality Authority (HIQA)
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Purpose: To evaluate the evidence of the effectiveness and safety of allografts compared to autografts in posterior cruciate ligament reconstruction.
Cecilia de Villiers, M.Sc., B.Sc. +3 more
doaj +1 more source
Background Continuity of care is considered important for results of treatment of serious mental illness (SMI). Yet, evidence of associations between relational continuity and different medical and social outcomes is sparse.
Ingemar Engström +8 more
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Objectives To identify research priorities related to the diagnosis, treatment and management of lipoedema.Design This was a research question priority-setting that ensured the involvement of patients, relatives and healthcare professionals in all parts.
Sara Fundell +7 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Medical Technology Under Proposals To Increase Competition in Health Care [PDF]
A study by the Office of Technology Assessment (OTA) that considers the "implications for medical technology of increased competition in health care" (p. 3)
United States. Congress. Office of Technology Assessment.
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Health care technology assessment
Cover title: Health care technology ...
Policy Workshop on Health Care Technology Assessment (1988 : Hamilton, Ont.) +1 more
core +1 more source

