Results 51 to 60 of about 2,804,815 (317)

Decision-analytic modeling for early health technology assessment of medical devices – a scoping review

GMS German Medical Science, 2022
Objective: The goal of this review was to identify decision-analytic modeling studies in early health technology assessments (HTA) of high-risk medical devices, published over the last three years, and to provide a systematic overview of model purposes ...
Conrads-Frank, Annette, Schnell-Inderst, Petra, Neusser, Silke, Hallsson, Lára R., Stojkov, Igor, Siebert, Silke, Kühne, Felicitas, Jahn, Beate, Siebert, Uwe, Sroczynski, Gabi   +9 more
doaj   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior, Edmara Bazoni Soares Maia, Soad Fuentes‐Alabí, Courtney E. Sullivan, Monnie Abraham, Mauricio Maza, Liliana Vásquez Ponce, Regina Aparecida Garcia Lima   +7 more
wiley   +1 more source

Policy models for preventative interventions in cardiometabolic diseases: a systematic review

BMC Health Services Research
Background Cardiometabolic diseases (CMDs), including cardiovascular disease (CVD) and type 2 diabetes (T2DM), are major contributors to morbidity, mortality, and rising healthcare costs.
Septiara Putri, Giorgio Ciminata, Jim Lewsey, Hanin Farhana Binti Kamaruzaman, Yuejiao Duan, Claudia Geue   +5 more
doaj   +1 more source

Health technology assessment in Finland [PDF]

International Journal of Technology Assessment in Health Care, 2009
Since the 1990s, health policy makers in Finland have been supportive of evidence-based medicine and approaches to implement its results. The Finnish Office for Health Technology Assessment (Finohta) has grown from a small start in 1995 to a medium-sized health technology assessment (HTA) agency, with special responsibility in providing assessments to ...
Mäkelä, Marjukka, Roine, Risto P
openaire   +2 more sources

Surgical trial in traumatic intracerebral haemorrhage (STITCH) : A randomised controlled trial of early surgery compared with Initial conservative treatment [PDF]

, 2015
Funding This project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme.Peer reviewedPublisher ...
Boto, Brain Trauma Foundation, American Association of Neurological Surgeons (AANS), Briggs, Briggs, Broderick, Bullock, Campbell & Cochrane Economics Methods Group and the Evidence for Policy and Practice Information and Co-ordinating Centre (CCEMG – EPPI), Chesnut, Choksey, Department of Health (DH), Drummond, D’Avella, Fairbank, Francis, Gabbe, Gallbraith, Glick, Gregson, Hutchinson, Hutchinson, Kenyon, Kind, Kind, Lancaster, Manca, Mathiesen, Mendelow, Mendelow, Mendelow, Mendelow, Mendelow, Mendelow, Murray, National Institute for Health and Care Excellence (NICE), National Institute for Health and Care Excellence (NICE), Pettigrew, Prasad, Seelig, Siddique, Simon, Weinstein, World Bank, World Health Organization (WHO), Zumkeller   +43 more
core   +1 more source

Financial Burden Associated With Hospitalisation Among Families of Childhood Brain Tumours in Australia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim, Natalie Bradford, David Brain, Sameera Senanayake, Sanjeewa Kularatna, Kate Young, Christine Cashion, Tim Hassall, Susanna Cramb   +8 more
wiley   +1 more source

High-cost users still came to hospitals during the COVID-19 pandemic during first wave data in Thailand: secondary data analysis

BMC Public Health
Background The phenomenon of high-cost users (HCUs) in health care occurs when a small proportion of patients account for a large proportion of health care expenditures.
Picharee Karunayawong, Piyada Gaewkhiew, Myka Harun Sarajan, Chulathip Boonma, Rukmanee Butchon, Jarawee Sukmanee, Thanayut Saeraneesopon, Yot Teerawattananon, Wanrudee Isaranuwatchai   +8 more
doaj   +1 more source

Assessing the performance of health technology assessment (HTA) agencies: developing a multi-country, multi-stakeholder, and multi-dimensional framework to explore mechanisms of impact

Cost Effectiveness and Resource Allocation, 2021
Background Health technology assessment (HTA) agencies have an important role to play in managing the rising demands on health systems. However, creating and running such agencies potentially diverts resources from frontline services.
Robyn Millar, Alec Morton, Maria Vittoria Bufali, Sven Engels, Saudamini Vishwanath Dabak, Wanrudee Isaranuwatchai, Kalipso Chalkidou, Yot Teerawattananon   +7 more
doaj   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source