Results 51 to 60 of about 23,885,267 (262)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Descriptive analysis of COVID-19 epidemiological indicators and associated contextual factors in European countries

open access: yes, 2022
At the request of the Department of Health, HIQA undertook a descriptive analysis of epidemiological indicators in order to describe the burden of COVID-19 as it has occurred across a range of European countries from 1 January 2020 up to 30 November ...
Health Information and Quality Authority (HIQA)
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Comparative Effectiveness and Safety of Allografts and Autografts in Posterior Cruciate Ligament Reconstruction Surgery: A Systematic Review

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, 2020
Purpose: To evaluate the evidence of the effectiveness and safety of allografts compared to autografts in posterior cruciate ligament reconstruction.
Cecilia de Villiers, M.Sc., B.Sc.   +3 more
doaj   +1 more source

Relational continuity may give better clinical outcomes in patients with serious mental illness – a systematic review

open access: yesBMC Psychiatry, 2023
Background Continuity of care is considered important for results of treatment of serious mental illness (SMI). Yet, evidence of associations between relational continuity and different medical and social outcomes is sparse.
Ingemar Engström   +8 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Lipoedema research priorities: a Swedish priority-setting partnership for future treatment and diagnostic studies

open access: yesBMJ Open
Objectives To identify research priorities related to the diagnosis, treatment and management of lipoedema.Design This was a research question priority-setting that ensured the involvement of patients, relatives and healthcare professionals in all parts.
Sara Fundell   +7 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Medical Technology Under Proposals To Increase Competition in Health Care [PDF]

open access: yes, 1982
A study by the Office of Technology Assessment (OTA) that considers the "implications for medical technology of increased competition in health care" (p. 3)
United States. Congress. Office of Technology Assessment.
core  

Health care technology assessment

open access: yes, 1989
Cover title: Health care technology ...
Policy Workshop on Health Care Technology Assessment (1988 : Hamilton, Ont.)   +1 more
core   +1 more source

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