Results 71 to 80 of about 979,842 (317)

Medical Technology Under Proposals To Increase Competition in Health Care [PDF]

open access: yes, 1982
A study by the Office of Technology Assessment (OTA) that considers the "implications for medical technology of increased competition in health care" (p. 3)
United States. Congress. Office of Technology Assessment.
core  

Health technology assessment and haemophilia

open access: yesHaemophilia, 2012
Summary.  Although the funding of rare diseases such as haemophilia in developing countries remains a low priority, pressures on the funding of haemophilia treatment are also emerging in developed economies affected by the global economic downturn and the other demands on health care budgets.
Farrugia, Albert, O'Mahony, B, Cassar, J
openaire   +3 more sources

The Health of the Scientific and Technical Enterprise: An Advisory Panel Report to the Office of Technology Assessment [PDF]

open access: yes, 1978
A report by the Office of Technology Assessment (OTA) on the science and technology fields, with the intent of developing a definition of the enterprise and giving "a framework within which policy makers can assess its health" (p. 3)
United States. Congress. Office of Technology Assessment.
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Introducing health technology assessment in Tanzania

open access: yes, 2019
Objectives Health technology assessment (HTA) is a cost-effective resource allocation tool in healthcare decision-making processes; however, its use is limited in low-income settings where countries fall short on both absorptive and technical capacity ...
Surgey, G   +11 more
core   +1 more source

Perception of vulnerable populations of label warnings in Global Adult Tobacco Survey (GATS) - Panama

open access: yesTobacco Induced Diseases, 2018
Background Tobacco products consumption is responsible of 148.6 million DALYS and 6.4 million deaths around the World in 2015, due to a large array associated medical conditions.
Hedley Knewjen Quintana   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Systematic review of economic evaluations of laparoscopic surgery for colorectal cancer [PDF]

open access: yes, 2008
Objective Colorectal cancer is one of the most common cancers and the standard surgical treatment for this cancer is open resection (OS), but laparoscopic surgery (LS) may be an alternative treatment.
Fraser, Cynthia Mary   +4 more
core   +1 more source

Improving the monitoring of chronic heart failure in Argentina: is the implantable pulmonary artery pressure with CardioMEMS Heart Failure System cost-effective?

open access: yesCost Effectiveness and Resource Allocation, 2021
Background The CardioMEMS® sensor is a wireless pulmonary artery pressure device used for monitoring symptomatic heart failure (HF). The use of CardioMEMS was associated with a reduction of hospitalizations of HF patients, but the acquisition cost could ...
Andrea Alcaraz   +6 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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