Results 91 to 100 of about 2,619,333 (310)
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
More than 4000 Indigenous Australian students enrol and take up a placement at boarding school each year. While reasons for attending boarding school vary, the impetus for many remote and very remote-dwelling students is restricted secondary educational ...
Michelle Redman-MacLaren +9 more
doaj +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Adult mortality and nutrition in rural Senegal: evidence of an epidemiologic transition
Background Global mortality transitions are driven by the epidemiologic transition, resulting in a rise in non-communicable diseases (NCDs), which are partly shaped by the nutrition transition and associated chronic conditions.
Lucie Vanhoutte +4 more
doaj +1 more source
Rural Zambian Oral Health Transition: A Long-Term Retrospective Examination of an Outreach Program's Progress and Impact. [PDF]
Morgan JP +4 more
europepmc +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
SES Health Gradients during the Epidemiological Transition: The Case of China [PDF]
The epidemiological transition, which has already passed the developed world, is still progressing in many developing countries. A particular problem associated with this transition is the under-diagnosis and lack of treatment of chronic diseases, and ...
Lei, Xiaoyan, Yin, Nina, Zhao, Yaohui
core +3 more sources
Se presentan las tendencias internacionales del cuidado de enfermería, que están cambiando a un ritmo inesperado a nivel internacional. El envejecimiento, las consecuencias de la urbanización y globalización aceleran la propagación de las enfermedades ...
Ángela María Salazar Maya
doaj

