Results 121 to 130 of about 13,430,401 (352)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Rural Zambian Oral Health Transition: A Long-Term Retrospective Examination of an Outreach Program's Progress and Impact. [PDF]

Ann Glob Health, 2023
Morgan JP, Marino ON, Finkelman M, Mourão CF, Flubinda FS.   +4 more
europepmc   +1 more source

Health transition in Africa: practical policy proposals for primary care.

Bulletin of the World Health Organization, 2010
Sub-Saharan Africa is undergoing health transition as increased globalization and accompanying urbanization are causing a double burden of communicable and noncommunicable diseases.
D. Maher, L. Smeeth, J. Sekajugo
semanticscholar   +1 more source

Connected by 25: Financing Policies and Practices that Support Permanency For Youth Transitioning Out of Foster Care [PDF]

, 2010
In an effort to strengthen philanthropic investments among its membership, the Youth Transition Funders Group (YTFG) asked a group of policy experts to provide recommendations on how foundations can work to encourage effective policy solutions on issues ...
Soumya Bhat, Torey Silloway
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Editorial: Mind the Gap! Criminal justice and health transitions for those with severe mental illness

Frontiers in Psychiatry, 2023
Charlotte Lennox, Beth Angell, Kimberlie Dean, Kimberlie Dean   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Causes and Trends of Mortality Among Iranian Older Adults From 2000 to 2019 [PDF]

Sālmand
Objectives Mortality statistics are among the important health indicators. Despite some studies on the mortality of Iranian older adults, these are not adequately considered compared with other demographic groups.
Arya Hamedanchi, Fereshteh Rezaie, Ayoub Nafei, Hamid Hamzezadeh   +3 more
doaj  

Erratum: Navigating disrupted puberty: Development and evaluation of a mobile-health transition passport for Klinefelter syndrome. [PDF]

Front Endocrinol (Lausanne), 2023
Frontiers Production Office.
europepmc   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source