Results 141 to 150 of about 13,430,401 (352)

Navigating Disrupted Puberty: Development and Evaluation of a Mobile-Health Transition Passport for Klinefelter Syndrome. [PDF]

Front Endocrinol (Lausanne), 2022
Dwyer AA, Héritier V, Llahana S, Edelman L, Papadakis GE, Vaucher L, Pitteloud N, Hauschild M.   +7 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Epidemiology of chronic multimorbidity and temporary migration in a rural South African community in health transition: A cross-sectional population-based analysis. [PDF]

Front Epidemiol, 2023
Dzomba A, Ginsburg C, Kabudula CW, Yorlets RR, Ndagurwa P, Harawa S, Lurie MN, McGarvey ST, Tollman S, Collinson MA, White MJ, Gomez-Olive FX.   +11 more
europepmc   +1 more source

Systematic review of transition models for young people with long-term conditions: A report for NHS Diabetes. [PDF]

, 2013
Aims For many young people with Type 1 diabetes, transition from paediatric to adult care can result in a marked deterioration in glycaemic control.
Bagnall, A, Day, R, Kime, NH
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Tendencias internacionales del cuidado de Enfermería Tendências internacionais do cuidado de enfermagem International trends in nursing care

Investigación y Educación en Enfermería, 2011
Se presentan las tendencias internacionales del cuidado de enfermería, que están cambiando a un ritmo inesperado a nivel internacional. El envejecimiento, las consecuencias de la urbanización y globalización aceleran la propagación de las enfermedades ...
Ángela María Salazar Maya
doaj  

Does Longevity Cause Growth [PDF]

This article challenges conventional wisdom by arguing that greater longevity cannot explain the significant accumulation of human capital during the transition from stagnation to growth.
Hosny Zoabi, Moshe Hazan
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Bringing Young People, Health and Social Care Professionals, Transition Champions and Policymakers Together Through Hybrid Methods of Participation: Creating a Space for Shared Understanding of What Is Required to Improve Young People's Healthcare Transition

Health Expectations
Introduction A multi‐stakeholder conference was held in 2023, celebrating the achievements of the Burdett National Transition Nursing Network (BNTNN).
Louise Porter, Faith Gibson, Susie Aldiss, Sue Morgan, Alexandra Stanton, Stella Carney, Aishah Farooq, Isabel Barlow, Haris Sultan, Pippa Sipanoun   +9 more
doaj   +1 more source

Young people who have fallen through the mental health transition gap: a qualitative study on primary care support. [PDF]

Br J Gen Pract, 2022
Appleton R, Loew J, Mughal F.
europepmc   +1 more source