Results 151 to 160 of about 10,030,185 (350)
Employee Health Insurance Decisions In a Flexible Benefits Environment [PDF]
, 1992 Empirical investigations of flexible benefits plans, an increasingly popular type of plan that allows employees to choose among multiple benefits options, have been limited. This study investigates hypotheses relating to the determinants of employees\u27
Barringer, Melissa W. +2 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Generic Health Utility Measures in Exercise Oncology: A Scoping Review and Future Directions. [PDF]
Curr Oncol, 2023 Parkinson JF +4 more
europepmc +1 more source
A new preference reversal in health utility measurement [PDF]
A central assumption in health utility measurement is that preferences are invariant to the elicitation method that is used. This assumptioin is challenged by preferences reversals.
Han Bleichrodt, Jose Luis Pinto-Prades
core
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Impact of surgical-site infection on health utility values: a meta-analysis. [PDF]
Br J Surg, 2023 McFarland AM +3 more
europepmc +1 more source
Why the Linear Utility Function is a Risky Choice in Discrete-Choice Experiments [PDF]
This article assesses how the form of the utility function in discrete-choice experiments (DCEs) affects estimates of willingness-to-pay (WTP). The utility function is usually assumed to be linear in its attributes.
Michele Sennhauser
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Populating an economic model with health state utility values: moving towards better practice [PDF]
Background: When estimating health state utility values (HSUV) for multiple health conditions, the alternative models used to combine these data can produce very different values.
Ara, Roberta, Brazier, John
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source