Results 131 to 140 of about 793,394 (367)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Health physics workforce in the United States [PDF]

, 2022
Michael A. Noska, Caridad Borrás, E. Vincent Holahan, Shaheen Dewji, Thomas E. Johnson, Jerry W. Hiatt, Wayne Newhauser, J.W. Poston, Nolan E. Hertel   +8 more
openalex   +1 more source

How Policy Variables Influence the Timing of Social Security Disability Insurance Applications - Policy Brief [PDF]

, 2001
While the onset of a health based work limitation will affect a worker’s ability to remain on the job, it does not necessarily result in a swift and certain job exit and transition onto the disability rolls.
Burkhauser, Richard V., Butler, J.S., Weathers II, Robert R   +2 more
core   +1 more source

The Health Workforce and Workforce Performance [PDF]

, 2003
Over the last ten years, performance management for health sector systems has received increased attention. In many countries privatisation, decentralisation, user involvement and cost containment have changed the structure and the functioning of health delivery dramatically. The role and performance of the workforce in the health sector has often been
openaire   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Occupational fall incidence associated with heated tobacco product use and lifestyle behaviors in Japan

Scientific Reports
This study identifies the association between heated tobacco product (HTP) use and occupational falls, considering lifestyle variables. A nationwide web-based cross-sectional study between September and November 2023 analyzed data from 18,440 workers in ...
Saki Tsushima, Kazuhiko Watanabe, Sora Hirohashi, Tomohiro Yoshimi, Yoshihisa Fujino, Takahiro Tabuchi, Masayoshi Zaitsu   +6 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Innovations that Address Socioeconomic, Cultural, and Geographic Barriers to Preventive Oral Health Care [PDF]

, 2013
This report focuses on nine oral health innovations that integrate service delivery and workforce models in order to reduce or eliminate socioeconomic, geographic, and cultural barriers to care.
D. Krol, K. Cheung, L. Carver, M. Revels, N. Dawkins-Lyn   +4 more
core  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Building faculty capacity for competency-based midwifery education in Rwanda - a cross-sectional study

BMC Medical Education
Background Competency-based education is globally recognized as the standard for preparing midwives to provide high-quality, evidence-based care. In 2024, Rwanda introduced a standardized, competency-based curriculum for midwifery education aligned with ...
Malin Bogren, Menelas Nkeshimana, Frida Temple, Marie Claire Iryanyawera, Darlene Ineza, Innocent Nzabahimana, Peninah Ingabire, Jean de Dieu Uwimana, Renata Tallarico, Olugbemiga Adelakin, Kerstin Erlandsson   +10 more
doaj   +1 more source