Results 101 to 110 of about 783,612 (311)

Understanding the genomic landscape of Klebsiella pneumoniae: insights into bacteraemia across North-West London hospitals between April 2020-December 2021

International Journal of Infectious Diseases
Introduction: Klebsiella pneumoniae is an opportunistic pathogen causing hospital-acquired antimicrobial-resistant (AMR) bacteraemia. The rise of multidrug-resistant strains of invasive K.
Mr Jonah Rodgus, Dr Maria Getino, Dr Yu Wan, Dr Frances Davies, Professor Alison Holmes, Dr Elita Jauneikaite   +5 more
doaj   +1 more source

The temporal trends and short‐ and long‐term mortality of people with acute myocardial infarction and rheumatoid arthritis: a nationwide cohort study

Arthritis Care &Research, Accepted Article.
Aims We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analysed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalised with AMI between 2005 and 2019 from the MINAP registry, linked ...
Megan Butler, Nicholas Weight, Muhammad Rashid, Rodrigo Bagur, Purvi Parwani, Samantha Hider, Edward Roddy, Robert Butler, Mamas A Mamas   +8 more
wiley   +1 more source

Combinatorial Synthesis of Next Generation Water‐Soluble Quaternized N‐Halamine Oligomers with Long‐Lasting Antiviral Properties

Advanced Functional Materials, EarlyView.
A combinatorial library of dual‐functional antiviral oligomers incorporating N‐halamine and quaternary ammonium functionalities is developed for long‐lasting antiviral activity. The lead materials exhibit rapid and durable antiviral activity against SARS‐CoV‐2 variants and influenza H1N1, with 4 to 5 log reduction in viral copies at 5 mg mL−1 ...
Eid Nassar‐Marjiya, Konda Reddy Kunduru, Krishanu Ghosal, Luna Rizik, Nofar Atari, Mahran Daifa, Neta Kutner, Bassma Khamaisi, Qi Wu, Simran Jindal, Merna Shaheen‐Mualim, Ranabir Majumder, Mahitosh Mandal, Michal Mandelboim, Shady Farah   +14 more
wiley   +1 more source

‘Caveat emptor’: the cautionary tale of endocarditis and the potential pitfalls of clinical coding data—an electronic health records study

BMC Medicine, 2019
Background Diagnostic codes from electronic health records are widely used to assess patterns of disease. Infective endocarditis is an uncommon but serious infection, with objective diagnostic criteria. Electronic health records have been used to explore
Nicola Fawcett, Bernadette Young, Leon Peto, T. Phuong Quan, Richard Gillott, Jianhua Wu, Chris Middlemass, Sheila Weston, Derrick W. Crook, Tim E. A. Peto, Berit Muller-Pebody, Alan P. Johnson, A. Sarah Walker, Jonathan A. T. Sandoe   +13 more
doaj   +1 more source

Hoitoon liittyvät infektiot ja niiden ehkäisy sairaalassa : testilista traumatologian ja nivelkirurgian yksiköiden sairaanhoitajille [PDF]

, 2015
Jokaisella potilaalla on oikeus saada laadultaan hyvää terveyden- ja sairaanhoitoa. Kuitenkin sairaalaan osastohoi-toon tulevista potilaista noin 5 % saa hoitoon liittyvän infektion.
Kettunen, Anna-Liisa
core  

Infection in prosthetic material [PDF]

, 2015
Surgical site infection (SSI) occurs when a wound created as part of a surgical procedure becomes infected. SSI is one of the most common healthcare-associated infections and occurs in approximately 5% of patients undergoing a surgical procedure. SSI may
Chetter, Ian, Smith, George
core   +1 more source

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source

Public Health Infection Prevention Mentorship Program for Philadelphia Skilled Nursing Facilities Utilizing a Health Equity Framework

Antimicrobial Stewardship & Healthcare Epidemiology
Background: Skilled nursing facilities (SNFs) face many challenges implementing robust infection prevention and control (IPC) programs. The Philadelphia Department of Public Health (PDPH) partnered with APIC Consulting Services, a wholly owned subsidiary
Tiina Peritz, Nicole Brand, Jessica M Rice, Jenna Scully, Kathryn Hitchcock, DeAnn Richards, Jane M Gould   +6 more
doaj   +1 more source

Clostridium difficile trehalose metabolism variants are common and not associated with adverse patient outcomes when variably present in the same lineageResearch in context

EBioMedicine, 2019
Background: Clostridium difficile ribotype-027, ribotype-078, and ribotype-017 are virulent and epidemic lineages. Trehalose metabolism variants in these ribotypes, combined with increased human trehalose consumption, have been hypothesised to have ...
David W. Eyre, Xavier Didelot, Anthony M. Buckley, Jane Freeman, Ines B. Moura, Derrick W. Crook, Tim E.A. Peto, A. Sarah Walker, Mark H. Wilcox, Kate E. Dingle   +9 more
doaj   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source