Results 61 to 70 of about 4,326,271 (292)

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Framework of Social Customer Relationship Management in E-Health Services

open access: yes, 2012
Healthcare organization is implementing Customer Relationship Management (CRM) as a strategy for managing interactions with patients involving technology to organize, automate, and coordinate business processes.
Almunawar, Mohammad Nabil   +1 more
core   +2 more sources

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Primary Health Network critical success factors [PDF]

open access: yes
The Primary Health Network (PHN) program has the potential to make a significant positive difference in health outcomes for all Australians. PHN Discussion Paper #1 - Primary Health Network Critical Success Factors reflects on the lessons learnt from ...
Australian Healthcare and Hospitals Association
core  

Household Healthcare Spending in 2014 [PDF]

open access: yes, 2016
This Beyond the Numbers article uses 2014 CE data to examine household spending on healthcare and its components. The article first examines the relationship between healthcare spending and household pretax income and then the relationship between ...
Foster, Ann C
core   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

A Privacy Preserving Framework for RFID Based Healthcare Systems [PDF]

open access: yes, 2017
RFID (Radio Frequency IDentification) is anticipated to be a core technology that will be used in many practical applications of our life in near future. It has received considerable attention within the healthcare for almost a decade now. The technology’
Ahamed, Sheikh Iqbal   +2 more
core   +1 more source

TEACHING SIGN LANGUAGE FOR HEALTHCARE WITHIN A LANGUAGES FOR SPECIFIC PURPOSES FRAMEWORK [PDF]

open access: yesJournal of Languages for Specific Purposes, 2019
Languages for specific purposes is a subdiscipline of applied linguistics that looks at language learning and teaching for a specific education or training need.
Keren Cumberbatch
doaj  

A Decentralized Peer-to-Peer Remote Health Monitoring System

open access: yesSensors, 2020
Within the Internet of Things (IoT) and blockchain research, there is a growing interest in decentralizing health monitoring systems, to provide improved privacy to patients, without relying on trusted third parties for handling patients’ sensitive
Muhammad Salek Ali   +4 more
doaj   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

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