Results 81 to 90 of about 3,427,639 (305)
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Humanitarian Urology in LMIC: Lessons Learned
Société Internationale d’Urologie JournalUrologic healthcare in low- and middle-income countries is recognized to be underserved. The goal to improve urologic health outcomes for populations in these countries may be met through urologic humanitarian work, often brought about by aid workers ...
Arthur L. Burnett
doaj +1 more source
FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
The medical student of the future: redefining competencies in a transformative era
Frontiers in MedicineMedical education is undergoing a profound transformation, driven by rapid technological advances, evolving pedagogical strategies, and the shifting demands of healthcare systems globally. This article explores the historical evolution of medical student
João P. Miguez-Pinto +14 more
doaj +1 more source
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Nursing ReportsBackground: The healthcare sector is under increasing pressure due to an ageing population, rising multimorbidity, and a projected global workforce shortage of 10 million by 2030.
Renske Emicke +2 more
doaj +1 more source
Proceedings of the 4th International ICST Conference on Pervasive Computing Technologies for Healthcare, 2010 Patrick Bentsen +4 more
openaire +3 more sources
2017 National Healthcare Quality and Disparities Report: Introductions and methods [PDF]
This Introduction and Methods document provides background on the annual National Healthcare Quality and Disparities Report (QDR) and modifications that have occurred over time. This document includes an overview of the methods used to generate estimates,
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Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source