Results 91 to 100 of about 4,511,882 (288)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Healthcare

, 2020
Healthcare is the most complex area addressed in this book. It is a data-rich environment and data dependent. Often healthcare delivery is time critical; it experiences high demand and under surge conditions is reliant on individual or groups of human healthcare workers.
Faulkner, Alastair, Nicholson, Mark
openaire   +2 more sources

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Health Care Costs: A Primer [PDF]

, 2007
Summarizes available data on healthcare costs and the impact of spending growth on society, and explores why healthcare costs have grown over ...

core  

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Workplace violence in Italian healthcare organizations: A multicenter survey on prevention measures and incident reporting [PDF]

GIornale Italiano di Psicologia e Medicina del Lavoro
Introduction: Workplace violence in healthcare settings is a growing global concern, particularly for its detrimental effects on workers’ safety and the operational efficiency of healthcare organizations.
Jessika CAMATTI, Francesco CHIRICO, Franco PUGLIESE, Mario GIACOMAZZI, Piero BORGIA, Anna Maria MINICUCCI, Nicola PINELLI, Eva COLOMBO, Giovanni MIGLIORE   +8 more
doaj   +1 more source

Massachusetts Health Care Reform: Six Years Later [PDF]

, 2012
Examines Massachusetts' implementation of healthcare reform since 2006 and outcomes to date, including expansion of coverage, gains in access to care, ongoing issues with rising costs, and changes needed to comply with federal healthcare ...

core  

Children's Medicines in Tanzania: A National Survey of Administration Practices and Preferences. [PDF]

, 2013
The dearth of age-appropriate formulations of many medicines for children poses a major challenge to pediatric therapeutic practice, adherence, and health care delivery worldwide.
AN Sachs, Cameron T. Nutt, D Baguley, D Notterman, DC Knoppert, DM Taylor, E Ansah, Elia John Mmbaga, G Peacock, Gary J. Noel, H Zucker, Helga Naburi, Imti Choonara, J Breitkreutz, J Teng, JA Mennella, K Hoppu, K Hoppu, K Hoppu, Lisa V. Adams, M Gazarian, P Nahirya-Ntege, Rodrick Kisenge, S Beggs, S Hill, S MacLeod, Sienna R. Craig, SR Craig, SR Hill, Stephen P. Spielberg, T Nunn, Timothy Lahey, W Rodriguez   +32 more
core   +3 more sources

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Humanitarian Urology in LMIC: Lessons Learned

Société Internationale d’Urologie Journal
Urologic healthcare in low- and middle-income countries is recognized to be underserved. The goal to improve urologic health outcomes for populations in these countries may be met through urologic humanitarian work, often brought about by aid workers ...
Arthur L. Burnett
doaj   +1 more source