Results 111 to 120 of about 2,949,264 (318)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Towards an interoperable healthcare information infrastructure - working from the bottom up [PDF]

, 2006
Historically, the healthcare system has not made effective use of information technology. On the face of things, it would seem to provide a natural and richly varied domain in which to target benefit from IT solutions. But history shows that it is one of
Darlison, MW, Patterson, D, T. Austin, Austin, T, B. Modell, D. Kalra, Kalra, D, D. Ingram, D. Patterson, Ingram, D, M. W. Darlison, Modell, B   +11 more
core   +1 more source

Exploring the Opportunities and Challenges of Healthcare Innovation in UK Higher Education: A Narrative Review

Nursing Reports
Background: The healthcare sector is under increasing pressure due to an ageing population, rising multimorbidity, and a projected global workforce shortage of 10 million by 2030.
Renske Emicke, Ashley Shepherd, Dylan Powell   +2 more
doaj   +1 more source

Medicolegal issues in healthcare: Corporatisation of healthcare [PDF]

Scottish Medical Journal, 2021
openaire   +3 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Smart and Secure Healthcare with Digital Twins: A Deep Dive into Blockchain, Federated Learning, and Future Innovations

Algorithms
In recent years, cutting-edge technologies, such as artificial intelligence (AI), blockchain, and digital twin (DT), have revolutionized the healthcare sector by enhancing public health and treatment quality through precise diagnosis, preventive measures,
Ezz El-Din Hemdan, Amged Sayed
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

AI in Healthcare: Do Not Forget About Allied Healthcare [PDF]

Artificial intelligence, the simulation of human intelligence by computers and machines, has found its way into healthcare, helping surgeons, doctors, radiologists, and many more.
Mark Scheper, Tim Hulsen
core   +1 more source

Lightweight Hybrid Cryptography Algorithm for Wireless Body Area Sensor Networks Using Cipher Technique

Computer Assisted Methods in Engineering and Science
Wireless Body Area Networks (WBANs) are based on connected and dedicated sensor nodes for patient monitoring in the healthcare sector. The sensor nodes are implanted inside or outside the patient’s body for sensing the vital signs and transmitting the ...
Aizaz Raziq, Kashif Naseer Qureshi, Asfand Yar, Kayhan Zrar Ghafoor, Gwanggil Jeon   +4 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source