Results 121 to 130 of about 2,949,264 (318)

Who's Going Broke? Comparing Growth in Healthcare Costs in Ten OECD Countries [PDF]

open access: yes
Government healthcare expenditures have been growing much more rapidly than GDP in OECD countries. For example, between 1970 and 2002 these expenditures grew 2.3 times faster than GDP in the U.S., 2.0 times faster than GDP in Germany, and 1.4 times ...
Laurence Kotlikoff, Christian Hagist
core  

Attitudes of Healthcare workers towards HIV patients [PDF]

open access: yes, 2016
The aim of this study was to evaluate the attitude of healthcare workers towards HIV/AIDS patients in Nigeria. In recent times, HIV/AIDS epidemic is now one of the major issues in public health, and the sub-Saharan part of Africa has been significantly ...
Jane, Ani
core  

Using implementation science to understand the implementation factors in a rural Produce Prescription program

open access: yesJournal of Agriculture, Food Systems, and Community Development
Produce Prescription programs (PPRs), in which healthcare providers prescribe no- or low-cost produce, have shown promise in improving food security, health outcomes and produce consump­tion. However, research on essential implementa­tion components has
Sonja Mydels   +5 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

TinyML-Based Lightweight AI Healthcare Mobile Chatbot Deployment

open access: yesJournal of Multidisciplinary Healthcare
Anita Christaline Johnvictor,1 M Poonkodi,1 N Prem Sankar,1 Thinesh VS2 1School of Computer Science and Engineering, Vellore Institute of Technology, Chennai, Tamil Nadu, India; 2Arista Networks Pvt Ltd, Bangalore, IndiaCorrespondence: Anita Christaline ...
Johnvictor AC   +3 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

NHSN biovigilance component protocol [PDF]

open access: yes
The NHSN is a secure, internet-based surveillance system that integrates former CDC surveillance systems, including the National Nosocomial Infections Surveillance System (NNIS), National Surveillance System for Healthcare Workers (NaSH), and the ...
National Center for Emerging and Zoonotic Infectious Diseases (U.S.) Division of Healthcare Quality Promotion.
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Smart App and Wearable Device-Based Approaches for Contactless Public Healthcare for Adolescents in Korea

open access: yesApplied Sciences
In Korea, the Public Health Center Mobile Healthcare Project was implemented in 2016. This project utilizes Information and Communication Technology (ICT) and big data to establish a health-related service foundation and a healthcare service operation ...
Ji-Hoon Cho, Seung-Taek Lim
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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