Results 51 to 60 of about 58,674 (263)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Fuzzy adaptive resonance theory failure mode effect analysis non-healthcare setting for infectious disease: review [PDF]

, 2023
Fuzzy adaptive resonance theory (ART) is an ART network that is developed as one of the alternative methods to evaluate risk priority number (RPN) in failure mode and effect analysis (FMEA).
Hazrul, Mohamad Basri, Mohd. Zulhilmi, Firdaus Rosli, Kuryati, Kipli, Kasumawati, Lias, Chai, Chee Shee, Aysha, Samjun   +5 more
core   +1 more source

Research progress in the application of different management models in fall prevention of patients

Huli yanjiu, 2021
This paper reviewed the research progress of healthcare failure mode and effect analysis，Swiss cheese model，bundles of care model，multidisciplinary collaboration model，comprehensive unit⁃based safety program and so on in fall prevention of patients.It ...
LIU Yuxiu, SHANG Linping
doaj  

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

PROCESSO DE INSERÇÃO, MANUTENÇÃO E RETIRADA DE CATETER INTRAVENOSO PERIFÉRICO: ANÁLISE PREVENTIVA DE RISCOS

Cogitare Enfermagem, 2023
Objetivo: demonstrar a aplicabilidade da ferramenta Healthcare Failure Mode and Effect Analysis para analisar, preventivamente, os riscos relativos ao processo de inserção, manutenção e retirada de cateter intravenoso periférico. Método: estudo teórico,
Maryana da Silva Furlan, Amanda Saba, Simone Berger, Antônio Fernandes Costa Lima   +3 more
doaj   +1 more source

Analisis Risiko Berdasarkan Proses ISO 31000:2018 dengan Metode Healthcare Failure Mode and Effect Analysis (HFMEA) pada Instalasi Gawat Darurat (IGD) Rumah Sakit X [PDF]

, 2022
Terdapat peraturan mengenai pengelolaan risiko rumah sakit di Indonesia yaitu Peraturan Menteri Kesehatan Republik Indonesia No.66 Tahun 2016 yang mengharuskan rumah sakit memiliki pengelolaan risiko untuk menjamin keselamatan pasien, pegawai, dan ...
Arkania, Aulia Salma; Departemen Teknik Sistem dan Industri Institut Teknologi Sepuluh Nopember Surabaya, Gunarta, I Ketut; Departemen Teknik Sistem dan Industri Institut Teknologi Sepuluh Nopember Surabaya   +1 more
core   +4 more sources