Failure mode and effect analysis in the indwelling urinary catheterization process [PDF]
Revista Latino-Americana de EnfermagemObjective: to analyze potential risks in the adult indwelling urinary catheterization process. Method: exploratory, descriptive and evaluative research in a teaching hospital.
Caroline Zottele Piasentin Giacomini +4 more
doaj +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
A Study of Root Causes and Countermeasures for Clinical Inertia in Type 2 Diabetes Patients in Community Based on Healthcare Failure Mode and Effect Analysis Framework [PDF]
Zhongguo quanke yixueBackground Since 2009, community health management for type 2 diabetes mellitus (T2DM) has been significantly promoted and implemented as a national public health service program. However, the impact of clinical inertia, defined as failure to take timely
LI Dianjiang, PAN Enchun, WANG Miaomiao, SUN Zhongming, WEN Jinbo, FAN Hong, SHEN Chong
doaj +1 more source
Use of Failure Mode and Effect Analysis Methods in Pediatric and Adolescent Hospital Care-A Scoping Review [PDF]
Introduction: Adverse events (AEs) leading to harm to patients are prevalent across health care. However, a considerable share of AEs are preventable. Failure Mode and Effect Analysis (FMEA) has been effectively used to enhance patient safety and quality.
Tuominen, Outi +2 more
core +1 more source
Theory-Based Failure Modes and Effect Analysis for Medication Errors
, 2021 This article presents a hybrid decision-making approach to assigning different weights to risk factors and considering the uncertainty in the ranking process in the Failure Modes and Effect Analysis (FMEA) technique.
Dorosti, Shadi +4 more
core +1 more source
Healthcare Failure Mode and Effect Analysis (HFMEA) in Reducing Patient Safety Incidents Risk at Hospital: Literature Review [PDF]
, 2023 Patient safety is a priority in hospital services, but patient safety incidents such as adverse events frequently occur in hospitals. Healthcare Failure Mode and Effect Analysis (HFMEA) is one of the hospital’s strategies to reduce patient safety ...
Basabih, Masyitoh +1 more
core +1 more source
FEBS Open Bio, EarlyView.Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Cogitare Enfermagem, 2023 Objetivo: demostrar la aplicabilidad de la herramienta Healthcare Failure Mode and Effect Analysis para analizar, de forma preventiva, los riesgos relacionados con el proceso de inserción, mantenimiento y retirada de catéteres intravenosos periféricos.
Maryana da Silva Furlan +3 more
doaj +1 more source
Healthcare Failure Mode And Effect Analysis: Proses Pelayanan Operasi di Rumah Sakit [PDF]
, 2012 Background: Most of medical errors are preventable. Highnumber of adverse event and near miss cases in hospitalsindicate opportunity for improvement. Therefore, efforts toidentify potential risks, recognize event as early as possible,and set a barrier ...
Andarini, I. V. (Indiati)
core
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source