Results 91 to 100 of about 911,116 (309)

Psychological personality traits in healthy people with various types of fat tissue distribution

Кардиоваскулярная терапия и профилактика, 2005
Aim. To investigate psychological personality traits in relatively healthy people with various types of fat tissue distribution. Material and methods. The study included 482 clinically healthy males and females. Participants were divided into six groups,
A. I. Kodochigova, A. G. Martynova, V. F. Kirichuk   +2 more
doaj  

Ethnic differences in adiposity and diabetes risk – insights from genetic studies [PDF]

, 2020
Type 2 diabetes is more common in non-Europeans and starts at a younger age and at lower BMI cut-offs. This review discusses the insights from genetic studies about pathophysiological mechanisms which determine risk of disease with a focus on the role of
Bell, J.D., Bell, J.D., Thomas, E.L., Thomas, E.L., Whitcher, B., Whitcher, B., Yaghootkar, H., Yaghootkar, H.   +7 more
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Weight-height relationship in girls with normal body fat content - Turner's syndrome vs. healthy short-statured [PDF]

Pediatric Endocrinology, Diabetes and Metabolism, 2009
Introduction: Turner’s syndrome is characterised by severely deficient body height and distorted body proportions as compared with healthy girls.
Edyta Sienkiewicz-Dianzenza, Katarzyna Milde, Paweł Tomaszewski, Romuald Stupnicki   +3 more
doaj  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Analysis of body composition characteristics in patients with type 1 diabetes mellitus: a case–control study based on a bioelectrical impedance analyzer

Frontiers in Medicine
ObjectiveThis study aimed to systematically compare differences in body composition between adult patients with type 1 diabetes mellitus (T1DM) and healthy controls using the bioelectrical impedance analysis (BIA) method, to provide an objective basis ...
Lun Zhang, Jiani Zhu, Ran Gu, Tongfen Cui, Xiaoyun Xi, Luying Yang, Guang Yu, Ji-Gan Wang, Fan Yang   +8 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Preliminary analysis of interaction of the fat fraction in the sacroiliac joint among sex, age, and body mass index in a normal Chinese population

Journal of International Medical Research, 2020
Objective Iterative decomposition of water and fat with echo asymmetry and least-squares estimation-iron quantification (IDEAL-IQ) is a noninvasive and objective method used to quantitatively measure fat content.
Qiuping Ning, Tiebing Fan, Jinyang Tang, Shuhua Han, Wensheng Wang, Hua Ren, Haiyi Wang, Huiyi Ye   +7 more
doaj   +1 more source

Modeling the Impact of Fat Flexibility With Dairy Food Servings in the 2015–2020 Dietary Guidelines for Americans Healthy U.S.-Style Eating Pattern

Frontiers in Nutrition, 2020
Background: The 2015–2020 Dietary Guidelines for Americans (DGA) recommends consuming low-fat or fat-free dairy foods due to concerns about energy and saturated fat intake.
Julie M. Hess, Christopher J. Cifelli, Victor L. Fulgoni   +2 more
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source