Results 131 to 140 of about 290,082 (288)
Algorithm for decomposition of differences between aggregate demographic measures and its application to life expectancies, healthy life expectancies, parity-progression ratios and total fertility rates [PDF]
A general algorithm for the decomposition of differences between two values of an aggregate demographic measure in respect to age and other dimensions is proposed.
Alexander Z. Begun +2 more
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
BMC Public HealthThe relationship between adherence to various healthy dietary patterns and life expectancy among US adults remained unclear. This study analyzed a representative sample of individuals aged 18 and older, selected from the National Health and Nutrition ...
Wei Tian +11 more
doaj +1 more source
International Journal of Public HealthObjectivesOur objective was to assess morbidity trends in Europe and to classify European countries based on population ageing theories: the compression, expansion and dynamic equilibrium of morbidity.MethodsThe proportions of healthy life years were ...
Jakub Straka +3 more
doaj +1 more source
Health and Wellness: Black Facts [PDF]
, 2015 Every year approximately 85,000 African American deaths are attributed to the Black – White mortality gap. Racial disparities in health in the United States are substantial. Today, death rates for African Americans remain 40% higher than for whites. They
core
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Regional differences in multidimensional aspects of health: findings from the MRC cognitive function and ageing study. [PDF]
, 2011 BACKGROUND: Differences in mortality and health experience across regions are well recognised and UK government policy aims to address this inequality.
Brayne, Carol +4 more
core
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Goals for the Common Good: Exploring the Impact of Education [PDF]
, 2009 Those who advocate for greater investment in education often make the economic argument: more education leads to higher wages and is critical for financial stability and independence. They're right. Robust evidence supports the view that higher levels of
Eduardo Borges Martins +3 more
core
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source