Results 81 to 90 of about 437,610 (188)
Relation of the Weibull Shape Parameter with the Healthy Life Years Lost Estimates: Analytic Derivation and Estimation from an Extended Life Table [PDF]
arXiv, 2019 Matsushita et al (1992) have done an interesting finding. They observed that the shape parameter of the Weibull model presented systematic changes over time and age when applied to mortality data for males and females in Japan. They have also estimated that this parameter was smaller in the 1891-1898 data in Japan compared to the 1980 mortality data ...
arxiv
Long-Term therapeutic effects of Katona therapy in moderate-to-severe perinatal brain damage [PDF]
arXiv, 2020 Aim: To determine the long-term efficacy of Katona therapy and early rehabilitation of infants with moderate-to-severe perinatal brain damage (PBD). Methods: Thirty-two participants were recruited (7-to-16 years) and divided into 3 groups: one Healthy group (n = 11), one group with PBD treated with Katona methodology from 2 months of corrected age, and
arxiv
Molecular Oncology, EarlyView.The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang +3 more
wiley +1 more source
Do You Live a Healthy Life? Analyzing Lifestyle by Visual Life Logging [PDF]
arXiv, 2020 A healthy lifestyle is the key to better health and happiness and has a considerable effect on quality of life and disease prevention. Current lifelogging/egocentric datasets are not suitable for lifestyle analysis; consequently, there is no research on lifestyle analysis in the field of computer vision.
arxiv
Molecular Oncology, EarlyView.Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa +13 more
wiley +1 more source
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
Molecular Oncology, EarlyView.We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock +10 more
wiley +1 more source
Healthy life expectancy in Europe
, 2013 International ...
Robine, Jean-Marie, Cambois, Emmanuelle
openaire +2 more sources
The journals of gerontology. Series B, Psychological sciences and social sciences, 2019 OBJECTIVES To examine changes in Healthy Life Expectancy (HLE) against the backdrop of rising mortality among less educated white Americans during the first decade of the 21st century. METHOD This study documented changes in HLE by education among U.S.
Phillip Cantu +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti +8 more
wiley +1 more source
Swimming with Wealthy Sharks: Longevity, Volatility and the Value of Risk Pooling [PDF]
arXiv, 2018 Who {\em values} life annuities more? Is it the healthy retiree who expects to live long and might become a centenarian, or is the unhealthy retiree with a short life expectancy more likely to appreciate the pooling of longevity risk? What if the unhealthy retiree is pooled with someone who is much healthier and thus forced to pay an implicit loading ...
arxiv