Results 81 to 90 of about 290,082 (288)
Trends in Working Life Expectancy in Europe [PDF]
, 2016 Objectives: The aim of the article is to analyze past and present developments of working life expectancy (WLE) at age 50 in Europe, by age and sex. Differences in WLE by education are explored as well.
Loichinger, E., Weber, D.
core +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Healthy life expectancy in Brazil: applying the Sullivan method [PDF]
Cadernos de Saúde Pública, 2005 The objective of this study is to present the method proposed by Sullivan and to estimate the healthy life expectancy using different measures of state of health, based on information from the World Health Survey carried out in Brazil in 2003. By combining information on mortality and morbidity into a unique indicator, simple to calculate and easy to ...
Romero, Dalia Elena +2 more
openaire +4 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
LIFE EXPECTANCY IN ROMANIA [PDF]
Risk in Contemporary Economy, 2014 In this research we can to observe the statistical modeling concerning the Life Expectancy in Romania, between 2000-2013, through by means of the „Least Squares Method”. The Life Expectancy reflects the average duration of the life concerning a person in
Gabriela OPAIT
doaj
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Self-perceived health in Belarus: Evidence from the income and expenditures of households survey [PDF]
Based on data from five cross-sectional household surveys conducted during 1996-2007, this study provides initial results of an analysis of self-perceived health in Belarus. The findings suggest that there has been a compression of morbidity.
Olga Grigorieva, Pavel Grigoriev
core
Healthy ageing: From a myth to a reality [PDF]
, 2016 The dream of living long and healthy has accompanied man since the beginning of time. The present remarkable increased life expectancy is most probably the result of better living conditions, medical progress, and better health care organization ...
BARBAGALLO, Mario +1 more
core +1 more source