Results 81 to 90 of about 8,055,040 (281)
Convergence or divergence of educational disparities in mortality and morbidity? The evolution of life expectancy and health expectancy by educational attainment in Austria in 1981-2006 [PDF]
The continuous increase in life expectancy in developed countries is typically associated with an increase in the number of years in good health, whereas the number of years in bad health rather stagnates.
Johannes Klotz
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
LIFE EXPECTANCY IN ROMANIA [PDF]
Risk in Contemporary Economy, 2014 In this research we can to observe the statistical modeling concerning the Life Expectancy in Romania, between 2000-2013, through by means of the „Least Squares Method”. The Life Expectancy reflects the average duration of the life concerning a person in
Gabriela OPAIT
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Healthy Life Expectancy in the EU Member States. ENEPRI Research Reports No. 33, July 2007. Revised version, originally published December 2006 [PDF]
, 2007 A shift in emphasis from increasing survival to improving both the length and quality of peoples’ lives has led to a greater policy interest in the United Kingdom and in Europe as a whole in summary measures of population health.
Weale, Martin., Khoman, Ehsan
core
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Demographic Research, 2002 A general algorithm for the decomposition of differences between two values of an aggregate demographic measure in respect to age and other dimensions is proposed.
doaj
A model for geographical variation in health and total life expectancy [PDF]
This paper develops a joint approach to life and health expectancy based on 2001 UK Census data for limiting long term illness and general health status, and on registered death occurrences in 2001.
Peter Congdon
core
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
SSM: Population Health, 2019 Obesity and smoking are the two leading causes of preventable death and disability in the United States. Both of these health risks are socially patterned in ways that likely produce racial/ethnic/nativity disparities in total and healthy life expectancy.
Michelle L. Frisco +2 more
doaj +1 more source