Results 81 to 90 of about 92,756 (241)

Past, Present, and Future of Healthy Life Expectancy.

Cold Spring Harbor perspectives in medicine, 2015
The success of the current biomedical paradigm based on a "disease model" may be limited in the future because of large number of comorbidities inflicting older people. In recent years, there has been growing empirical evidence, based on animal models, suggesting that the aging process could be delayed and that this process may lead to increases in ...
Beltrán-Sánchez, Hiram, Soneji, Samir, Crimmins, Eileen M   +2 more
openaire   +3 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Healthy life expectancy : is there convergence in Europe?

, 2021
Para avançar nosso conhecimento sobre convergência em saúde global, este estudo empregou dados de 31 países europeus para testar a hipótese de convergência do uso de dados de expectativa de vida em saúde (HLE) de 2004 a 2016. A convergência foi examinada por meio de diferentes perspetivas na literatura.
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Healthy life expectancy in Europe

, 2013
Each year since 2005, Eurostat has calculated life expectancy without activity limitations, known as"healthy life years". While life expectancy at age 65 increased by one year in the European Union between2005 and 2010, the years lived in poor perceived health decreased (by 0.5 years for men and 1.1 years for women)despite an increase in years with ...
Robine, Jean-Marie, Cambois, E
openaire   +2 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Older adults' beliefs about physician-estimated life expectancy: a cross-sectional survey

BMC Family Practice, 2006
Background Estimates of life expectancy assist physicians and patients in medical decision-making. The time-delayed benefits for many medical treatments make an older adult's life expectancy estimate particularly important for physicians.
Bynum Debra L, Amick Halle R, Lewis Carmen L, Kistler Christine E, Walter Louise C, Watson Lea C   +5 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Metropolitan inequalities in health system resources and COVID-19 adjusted life expectancy among older adults in Mexico

Frontiers in Public Health
IntroductionThe mortality and morbidity consequences of the COVID-19 outbreak were concentrated among older adults. The health system response was critical to mitigating its negative effects, particularly through the redistribution of healthcare ...
Héctor García-Hernández, Héctor García-Hernández, Guillermo Salinas-Escudero, Marcela Agudelo-Botero, Hortensia Reyes-Morales   +4 more
doaj   +1 more source

Healthy life expectancy: comparison of OECD countries in 2001

Australian and New Zealand Journal of Public Health, 2003
Objectives: To compare average levels of population health for Australia and other OECD countries in 2001. Methods: Healthy life expectancies (HALE) for OECD countries for 2001 are based on analysis of mortality data for OECD countries, country‐specific ...
Colin D. Mathers, Christopher J.L. Murray, Joshua A. Salomon, Ritu Sadana, Ajay Tandon, Alan D. Lopez, Bedirhan Ustün, Somnath Chatterji   +7 more
doaj   +1 more source