Results 131 to 140 of about 1,153,162 (300)
he Health of the Economy as a Living Organism [PDF]
Theoretical and Applied Economics, 2010 According to “the health of the common living whole”, economy is a living organism, part of the human society, with which it is integrated in our microcosm environment. As organic component of the living, economy has as a viability criterion of its sense
Constantin POPESCU, Cristina BURGHELEA
doaj
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Do Employees From Less-Healthy Communities Use More Care and Cost More? Seeking to Establish a Business Case for Investment in Community Health. [PDF]
, 2019 INTRODUCTION: Few studies have examined the impact of community health on employers. We explored whether employed adults and their adult dependents living in less-healthy communities in the greater Philadelphia region used more care and incurred higher ...
Alonzo, Greg +7 more
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Active Living: Promoting Physical Activity through Healthy Environments
, 2017 Rapid urbanization poses significant public health challenges. By designing activity-friendly environments, designers and planners canenable people to be physically active in their daily routines and shape fundamental aspects of health and well being.
openaire +1 more source
Biourbanism for a healthy city: biophilia and sustainable urban theories and practices [PDF]
, 2012 The paper was given via audio/slides file on 4th September 2012 in the International Convention on Innovations in Engineering and Technology for Sustainable Development, 3-5 September 2012, in Bannari Amman Institute of Technology, Erode District, Tamil ...
Caperna, Antonio, Tracada, Eleni
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Cohort Profile: Growing Up in Wales: The Environments for Healthy Living study [PDF]
International Journal of Epidemiology, 2015 Morgan, Kelly +4 more
openaire +6 more sources