Results 1 to 10 of about 434,662 (294)

E2F/Rb Family Proteins Mediate Interferon Induced Repression of Adenovirus Immediate Early Transcription to Promote Persistent Viral Infection. [PDF]

open access: yesPLoS Pathogens, 2016
Interferons (IFNs) are cytokines that have pleiotropic effects and play important roles in innate and adaptive immunity. IFNs have broad antiviral properties and function by different mechanisms. IFNs fail to inhibit wild-type Adenovirus (Ad) replication
Yueting Zheng   +2 more
doaj   +1 more source

An MR spectroscopy study of temporal areas excluding primary auditory cortex and frontal regions in subjective bilateral and unilateral tinnitus

open access: yesScientific Reports, 2023
Previous studies indicate changes in neurotransmission along the auditory pathway in subjective tinnitus. Most authors, however, investigated brain regions including the primary auditory cortex, whose physiology can be affected by concurrent hearing ...
Joanna Wójcik   +8 more
doaj   +1 more source

Posttraumatic Growth in Postlingually Deaf Patients With Cochlear Implants: The Effect of Stress-Coping Strategies, Sociodemographics, and Deafness-Related Factors

open access: yesFrontiers in Psychology, 2021
The aim of this study was to assess whether cochlear implant (CI) users who had been postlingually deaf developed a more positive outlook on life—the so-called posttraumatic growth (PTG)—as a result of their disability and to examine how PTG related to ...
Joanna Kobosko   +10 more
doaj   +1 more source

Using the phase inversion method and loudness comparisons for the evaluation of noise reduction algorithms in hearing aids

open access: yesActa Acustica, 2021
The phase inversion method, a technical measurement procedure, is often used to evaluate the performance of noise reduction algorithms in hearing aids. However, a detailed comparison of these technical measurements with the perceived loudness is missing.
Husstedt Hendrik   +6 more
doaj   +1 more source

Psychometric properties of the Polish version of the Children’s Auditory Performance Scale

open access: yesMedycyna Ogólna i Nauki o Zdrowiu, 2020
Introduction and objectives. The key element of the diagnostics of Auditory Processing Disorder (APD) is assessment of peripheral hearing and higher auditory functions, supplemented by information from clinical history-taking.
Katarzyna Bieńkowska   +2 more
doaj   +1 more source

Mechanism of Adenovirus E4-ORF3-Mediated SUMO Modifications

open access: yesmBio, 2019
Regulation of a variety of different cellular processes, including posttranslational modifications, is critical for the ability of many viruses to replicate efficiently within host cells.
Sook-Young Sohn, Patrick Hearing
doaj   +1 more source

Adenovirus Early Proteins and Host Sumoylation

open access: yesmBio, 2016
The human adenovirus genome is transported into the nucleus, where viral gene transcription, viral DNA replication, and virion assembly take place. Posttranslational modifications by small ubiquitin-like modifiers (SUMOs) are implicated in the regulation
Sook-Young Sohn, Patrick Hearing
doaj   +1 more source

Persistent Stapedial Artery Encountered during Cochlear Implantation

open access: yesCase Reports in Otolaryngology, 2022
Objectives. Persistent stapedial artery (PSA) is a rare congenital anomaly that can complicate middle ear surgery. Methods. We present the case of a 25-year-old male who underwent right-sided cochlear implantation.
Holly Jones   +6 more
doaj   +1 more source

Clinically important change in tinnitus sensation after stapedotomy

open access: yesHealth and Quality of Life Outcomes, 2018
Background When measuring the treatment effect in tinnitus with multi-item outcome instruments, it is crucial for both clinical and research purposes to take into consideration clinical importance of the outcome scores. The aim of the present study is to
Henryk Skarżyński   +5 more
doaj   +1 more source

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