Results 101 to 110 of about 2,269,019 (331)
Interactions of Interaural Time and Level Differences in Spatial Hearing with Cochlear Implants
Advanced Science, EarlyView.Differences in timing (ΔT) are weighted heavily compared to differences in loudness (ΔL) in binaural hearing with cochlear implants. Abstract Normally hearing humans can localize sound sources quite accurately, with minimum audible angles as small as 1°. To achieve this, these auditory pathways combine information from multiple acoustic cues, including
Sarah Buchholz +3 more
wiley +1 more source
Advanced Science, EarlyView.This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun +15 more
wiley +1 more source
Advanced Science, EarlyView.This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin S. George, Anthony J. Ricci
wiley +1 more source
Electrical Control of the Transduction Channels’ Gating Force in Mechanosensory Hair Cells
Advanced Science, EarlyView.The inner ear's hair cells rely on mechanosensitive ion channels to convert vibrations of their hair‐bundle into electrical signals. We show that varying the electrical potential (U) across the sensory epithelium modulates a key determinant of mechanosensitivity—the gating force (FG)—by modulating the gating swing (d), ranging from the size of the ...
Achille Joliot +2 more
wiley +1 more source
Persistent Olfactory and Taste Dysfunction after COVID-19
Life(1) Background: One of the possible symptoms of COVID-19 is a sudden loss of smell and taste. The main aim of the study was to evaluate the severity of post-COVID-19 olfactory dysfunction (OD).
Malgorzata Buksinska +4 more
doaj +1 more source
XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss
Advanced Science, EarlyView.Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan +13 more
wiley +1 more source
Impact of Language Barriers and Age on English Hearing Test App Accuracy for Polish Users
OTO OpenObjective The development of health applications (apps) includes those for testing hearing, although most of them are available only in English. This study investigates whether poor English language proficiency creates a barrier for Polish users in the ...
Małgorzata Pastucha +3 more
doaj +1 more source
Non-Musicians Experience Early Aging in Speech Perception in Noise Abilities Compared to Musicians
Journal of OtologyBackgroundResearch has shown that musicians outperform non-musicians in speech perception in noise (SPiN) tasks. However, it remains unclear whether the advantages of musical training are substantial enough to slow down the decline in SPiN performance ...
Kruthika. S., Ajith Kumar Uppunda
doaj +1 more source
“Can you hear me now?”: Insurance Coverage for Hearing Benefits in the United States [PDF]
, 2015 Public and private insurance coverage for hearing benefits underscores the gaps in coverage for treating hearing loss in the U.S. The commodification of the hearing benefits sector of healthcare in this country has detrimental consequences for personal ...
Whipple, Reegan
core +1 more source