Results 11 to 20 of about 762,269 (339)

The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022
Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee   +16 more
wiley   +1 more source

Book review of “Here, there, everywhere—A memoir” by Peter Almond

open access: yes, 2022
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022.
Bruce J. Gerbi
wiley   +1 more source

Mechanism of Adenovirus E4-ORF3-Mediated SUMO Modifications

open access: yesmBio, 2019
Regulation of a variety of different cellular processes, including posttranslational modifications, is critical for the ability of many viruses to replicate efficiently within host cells.
Sook-Young Sohn, Patrick Hearing
doaj   +1 more source

Persistent Stapedial Artery Encountered during Cochlear Implantation

open access: yesCase Reports in Otolaryngology, 2022
Objectives. Persistent stapedial artery (PSA) is a rare congenital anomaly that can complicate middle ear surgery. Methods. We present the case of a 25-year-old male who underwent right-sided cochlear implantation.
Holly Jones   +6 more
doaj   +1 more source

Implantation of the Bonebridge BCI 602 after Mastoid Obliteration with S53P4 Bioactive Glass: A Safe Method of Treating Difficult Anatomical Conditions-Preliminary Results

open access: yesLife, 2021
This study presents the preliminary results of a new otosurgical method in patients after canal wall down (CWD) surgery; it involves the implantation of the Bonebridge BCI 602 implant after obliteration of the mastoid cavity with S53P4 bioactive glass ...
Bartłomiej Król   +3 more
doaj   +1 more source

Clinically important change in tinnitus sensation after stapedotomy

open access: yesHealth and Quality of Life Outcomes, 2018
Background When measuring the treatment effect in tinnitus with multi-item outcome instruments, it is crucial for both clinical and research purposes to take into consideration clinical importance of the outcome scores. The aim of the present study is to
Henryk Skarżyński   +5 more
doaj   +1 more source

Hear, Hear for the Zebrafish [PDF]

open access: yesNeuron, 2005
Our senses of hearing and balance rely on the function of specialized receptor neurons called "hair cells." In this issue of Neuron, Grant et al. report a series of elegant zebrafish experiments that reveal a previously unappreciated role for glia in the regulation of hair cell proliferation and differentiation.
openaire   +3 more sources

Hearing Loss and Depression in Older Adults: A Systematic Review and Meta-analysis.

open access: yesThe gerontologist, 2020
BACKGROUND AND OBJECTIVES Studies reporting an association between hearing loss and depression in older adults are conflicting and warrant a systematic review and meta-analysis of the evidence. RESEARCH DESIGN AND METHODS A search of academic databases
Blake J. Lawrence   +5 more
semanticscholar   +1 more source

Multi-Frequency Intraoperative Monitoring of Hearing Preservation during Cochlear Implantation

open access: yesLife, 2022
(1) Background: Current indications for cochlear implants (CIs) have expanded to include patients with appreciable low-frequency hearing. However, longitudinal results indicate that only one-third of these recipients retain full hearing preservation.
Piotr Henryk Skarżyński   +4 more
doaj   +1 more source

Clinical Practice Guideline: Sudden Hearing Loss (Update)

open access: yesOtolaryngology Head & Neck Surgery, 2019
Objective Sudden hearing loss is a frightening symptom that often prompts an urgent or emergent visit to a health care provider. It is frequently but not universally accompanied by tinnitus and/or vertigo.
S. Chandrasekhar   +17 more
semanticscholar   +1 more source

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