Results 101 to 110 of about 2,035,475 (362)

Impact of aging on the auditory system and related cognitive functions: A narrative review [PDF]

open access: yes, 2018
Age-related hearing loss (ARHL), presbycusis, is a chronic health condition that affects approximately one-third of the world’s population. The peripheral and central hearing alterations associated with age-related hearing loss have a profound impact on ...
Friedland, Peter L   +3 more
core   +3 more sources

Viral‐Mediated Connexin 26 Expression Combined with Dexamethasone Rescues Hearing in a Conditional Gjb2 Null Mice Model

open access: yesAdvanced Science, EarlyView.
AAV2.7m8 serotype combined with the gfaABC1D promoter targets infection of supporting cells (SCs). AAV2.7m8‐gfaABC1D‐Gjb2 administration to mice results in excessive immune responses. The combination of AAV2.7m8‐gfaABC1D‐Gjb2 with dexamethasone (DEX) shows a synergistic effect and enhances the gene therapy effect in a conditional Cx26 null mice model ...
Xiaohui Wang   +8 more
wiley   +1 more source

Analysis of video head impulse test saccades data in patients with vestibular migraine or probable vestibular migraine

open access: yesJournal of Otology, 2022
Objective: Saccades accompanied by normal gain in video head impulse tests (vHIT) are often observed in patients with vestibular migraine (VM). However, they are not considered as an independent indicator, reducing their utility in diagnosing VM.
Yi Du   +4 more
doaj  

The association of hearing impairment and its severity with physical and mental health among Chinese middle-aged and older adults

open access: yesHealth and Quality of Life Outcomes, 2020
Background Hearing impairment is a common chronic condition which can be closely related to people’s health. However, current studies on this topic are quite limited in developing countries, and few with standardized audiometric measurement and multiple ...
Xin Ye, Dawei Zhu, Siyuan Chen, Ping He
doaj   +1 more source

Exploiting Hidden Representations from a DNN-based Speech Recogniser for Speech Intelligibility Prediction in Hearing-impaired Listeners [PDF]

open access: yesarXiv, 2022
An accurate objective speech intelligibility prediction algorithms is of great interest for many applications such as speech enhancement for hearing aids. Most algorithms measures the signal-to-noise ratios or correlations between the acoustic features of clean reference signals and degraded signals.
arxiv  

Hearing Impairment and Incident Dementia: Findings from the English Longitudinal Study of Ageing

open access: yesJournal of The American Geriatrics Society, 2017
To determine whether hearing loss is associated with incident physician‐diagnosed dementia in a representative sample.
H. Davies   +4 more
semanticscholar   +1 more source

Hearing Impairment Caused by Noise at the Workplace [PDF]

open access: yes, 2021
Objectives: The aim of this article is to determine the prevalence of hearing impairment caused by noise among workers in two companies in Bosnia and Herzegovina, to correlate hearing loss with age and years of specific work experience, and to indicate ...
Milanovic, Ermina Sitnic-   +3 more
core   +1 more source

Programmable NIR Responsive Nanocomposite Enables Noninvasive Intratympanic Delivery of Dexamethasone to Reverse Cisplatin Induced Hearing Loss

open access: yesAdvanced Science, EarlyView.
In this study, saponin‐coated silica@gold nanocarriers responsive to NIR radiation is developed to enhance intratympanic drug delivery for cisplatin‐induced hearing loss (CIHL) treatment. The biocompatibility and oto‐protective properties are validated both in vitro and in vivo.
Rawand A. Mustafa   +6 more
wiley   +1 more source

OPA1-related auditory neuropathy: site of lesion and outcome of cochlear implantation. [PDF]

open access: yes, 2015
Hearing impairment is the second most prevalent clinical feature after optic atrophy in Dominant Optic Atrophy associated with mutations in the OPA1 gene.
Arslan, E   +12 more
core   +3 more sources

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

open access: yesAdvanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao   +14 more
wiley   +1 more source

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