Results 101 to 110 of about 338,619 (303)

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

The effect of right versus left long-term single-sided deafness on sound source localization

Journal of Otology
Purpose: To analyze the effect of right versus left long-term single-sided deafness (SSD) on sound source localization (SSL), discuss the necessity of intervention and treatment for SSD patients, and analyze the therapeutic effect of long-term unilateral
Qingqing Xia, Shuoshuo Kang, Qian Wang, Mengdi Hong, Aiting Chen, Wei Chen, Fei Ji, Jianan Li, Shiming Yang   +8 more
doaj   +1 more source

Relationships between dipstick proteinuria and risk of hearing impairment among Japanese workers: a prospective cohort study

BMJ Open, 2019
Objectives Hearing impairment is among the most significant health problems, and the number of adults with hearing impairment is increasing worldwide. Therefore, the prevention of hearing impairment is important.
Mitsumasa Umesawa, Toshimi Sairenchi, Yasuo Haruyama, Gen Kobashi, Mikako Hara   +4 more
doaj   +1 more source

Evaluating long-latency auditory evoked potentials in the diagnosis of cortical hearing loss in children [PDF]

, 2016
In centrally related hearing loss, there is no apparent damage in the auditory system, but the patient is unable to hear sounds. In patients with cortical hearing loss (and in the absence of communication deficit, either total or partial, as in agnosia ...
López Soto, María Teresa, Núñez Abades, Pedro Antonio, Postigo Madueño, Amparo   +2 more
core   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

Functional characterization of MFSD3 in auditory system and zebrafish embryogenesis

Frontiers in Genetics
The solute carriers (SLCs) are important membrane-bound transporters that regulate cellular nutrition, metabolism, homeostasis and survival. Emerging evidence highlights the critical involvement of SLCs in auditory physiology.
Ying Ma, Ying Ma, Ying Ma, Ying Ma, Ying Ma, Shi-Wei Qiu, Shi-Wei Qiu, Wei-Qian Wang, Hai-Feng Feng, Hai-Feng Feng, Hai-Feng Feng, Hai-Feng Feng, Hai-Feng Feng, Lu Zheng, Lu Zheng, Lu Zheng, Lu Zheng, Lu Zheng, Ge-Ge Wei, Ge-Ge Wei, Ge-Ge Wei, Ge-Ge Wei, Ge-Ge Wei, Hui-Yi Nie, Hui-Yi Nie, Hui-Yi Nie, Hui-Yi Nie, Hui-Yi Nie, Jin-Yuan Yang, Jin-Yuan Yang, Jin-Yuan Yang, Jin-Yuan Yang, Jin-Yuan Yang, Yi-Jin Chen, Yi-Jin Chen, Yi-Jin Chen, Yi-Jin Chen, Yi-Jin Chen, Pu Dai, Pu Dai, Pu Dai, Pu Dai, Pu Dai, Xue Gao, Yong-Yi Yuan, Yong-Yi Yuan, Yong-Yi Yuan, Yong-Yi Yuan, Yong-Yi Yuan   +48 more
doaj   +1 more source

Osteogenesis imperfecta: the audiological phenotype lacks correlation with the genotype [PDF]

, 2011
Background: Osteogenesis Imperfecta (OI) is a heritable connective tissue disorder mainly caused by mutations in the genes COL1A1 and COL1A2 and is associated with hearing loss in approximately half of the cases.
Swinnen, Freya, Coucke, Paul, De Paepe, Anne, Symoens, Sofie, Malfait, Fransiska, Gentile, Filomena V, Sangiorgi, Luca, D'Eufemia, Patrizia, Celli, Mauro, Garretsen, Ton JTM, Cremers, Cor WRJ, Dhooge, Ingeborg, De Leenheer, Els   +12 more
core   +3 more sources

In Situ X‐Ray Tomography and Acoustic Emission Monitoring of Damage Evolution in C/C‐SiC Composites Fabricated by Liquid Silicon Infiltration

Advanced Science, EarlyView.
This study investigates how the internal structure of fiber‐reinforced ceramic composites affects their resistance to damage. By combining 3D X‐ray imaging with acoustic emission monitoring during mechanical testing, it reveals how silicon distribution influences crack formation.
Yang Chen, Renato S. M. Almeida, Stefan Flauder, Guillaume Couégnat, Kamen Tushtev, Jürgen Horvath, Peter Wriggers, Kurosch Rezwan   +7 more
wiley   +1 more source

Reversal of auditory cortical hyperexcitability and restoration of synaptic plasticity balance by GluN1-mediated photobiomodulation in noise-induced tinnitus

Brain Research Bulletin
Glutamate receptors regulate neuronal excitability and drive synaptic plasticity in the auditory cortex (AC), with aberrant activation or dysfunction contributing to tinnitus pathogenesis.
Zhixin Zhang, Xinmiao Xue, Dongdong He, Peng Liu, Chi Zhang, Yvke Jiang, Shuhan Lv, Li Wang, Hanwen Zhou, Weidong Shen, Shiming Yang, Fangyuan Wang   +11 more
doaj   +1 more source

Kemampuan Komunikasi Anak Tunarungu [PDF]

, 2011
This research aimed to find out the influencing differences of variables such as learning strategies and levels of deafness toward the verbal and non verbal communication ability in hearing impairment children. Besides, this research also aimed
Bintoro, T. (Totok)
core