Results 111 to 120 of about 2,067,463 (390)

Saccades of video head impulse test in Meniere's disease and Vestibular Migraine: What can we learn from?

Journal of Otology, 2023
Background: Saccades are often observed on video head impulse tests (vHIT) in patients with Meniere's Disease (MD) and Vestibular Migraine (VM). However, their saccadic features are not fully described. Objective: This study aims to identify the saccades
Yi Du, Xingjian Liu, Lili Ren, Yu Wang, Fei Ji, Weiwei Guo, Ziming Wu   +6 more
doaj  

Comparison of health related quality of life of primary school deaf children with and without motor impairment

Italian Journal of Pediatrics, 2010
Objective To compare the health-related quality of life (HRQOL) of primary school-age deaf children with or without motor impairment to that of typically developing peers. Methods This study was a prospective, cross sectional study.
Roy Finita, Rajendran Venkadesan
doaj   +1 more source

LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing

Advanced Science, EarlyView.
This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang, Yuehui Xi, Qiaojun Fang, Sai Shi, Fei Wang, Fuyu Xian, Zhongyang Zhang, Yuxin Yang, Xishuo Jin, Xiaomin Wang, Chen Cao, Hailin Zhang, Nikita Gamper, Zhigang Xu, Haitao Shen, Ping Lv   +15 more
wiley   +1 more source

The association of hearing impairment and its severity with physical and mental health among Chinese middle-aged and older adults

Health and Quality of Life Outcomes, 2020
Background Hearing impairment is a common chronic condition which can be closely related to people’s health. However, current studies on this topic are quite limited in developing countries, and few with standardized audiometric measurement and multiple ...
Xin Ye, Dawei Zhu, Siyuan Chen, Ping He
doaj   +1 more source

Exome Sequencing Reveals the Genetic Architecture of Non‐syndromic Orofacial Clefts and Identifies BOC as a Novel Causal Gene

Advanced Science, EarlyView.
Nonsyndromic orofacial clefts (NSOFCs) are the most common craniofacial defects. Exome sequencing of 214 sporadic cases sheds new light on its genetic architecture and identifies many candidate pathogenic variants. Furthermore, functional studies establish BOC as a novel causal gene and reveal an unusual two‐locus model of inheritance via the epistatic
Qing He, Min Yu, Yuhua Jiao, Yizhu Xu, Xuqin Liang, Wenbin Huang, Linping Xu, Yuxia Hou, Zhanping Ren, Beile Lyu, Zhenwei Qian, Pengpeng Liu, Jing Zhou, Huimei Huang, Chunyan Yin, Huaxiang Zhao, Yi Ding   +16 more
wiley   +1 more source

Hearing Impairment and Incident Dementia: Findings from the English Longitudinal Study of Ageing

Journal of The American Geriatrics Society, 2017
To determine whether hearing loss is associated with incident physician‐diagnosed dementia in a representative sample.
H. Davies, D. Cadar, A. Herbert, M. Orrell, A. Steptoe   +4 more
semanticscholar   +1 more source

Post‐Translational Modifications in Cilia and Ciliopathies

Advanced Science, EarlyView.
This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
wiley   +1 more source

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

Advanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang, Lixia Song, Rui Fan, Qianqian Chen, Ruisheng Fu, Mei You, Yuxiao Wu, Meng Cai, Yong Li, Meihong Xu   +9 more
wiley   +1 more source

Unilateral versus bilateral hearing aids for bilateral hearing impairment in adults [PDF]

, 2017
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of bilateral versus unilateral hearing aids in adults with a bilateral hearing ...
Browning, George G., Chong, Lee Yee, Ftouh, Saoussen, Howell, Patrick, Naylor, Graham, Whitmer, William M.   +5 more
core   +3 more sources

The prevalence of hearing impairment within the Cape Town Metropolitan area

South African Journal of Communication Disorders, 2016
Background: There is a lack of data on the prevalence of hearing impairment in South Africa. Current data is unreliable as it is based on national census information which tends to underestimate the prevalence of hearing impairment.
Lebogang Ramma, Ben Sebothoma
doaj   +1 more source