Results 131 to 140 of about 2,035,475 (362)

GDC: Integration of Multi‐Omic and Phenotypic Resources to Unravel the Genetic Pathogenesis of Hearing Loss

Advanced Science, EarlyView.
Overview of the Genetic Deafness Commons (GDC), integrating data from the Chinese Deafness Genetics Consortium (CDGC) and 51 public databases. The GDC provides tools for variant search, functional predictions, and gene‐disease visualization, offering insights into 201 hearing loss genes and facilitating novel gene discovery and clinical applications ...
Hui Cheng, Xuegang Wang, Mingjun Zhong, Jia Geng, Wenjian Li, Kanglu Pei, Jing Wang, Lanchen Wang, Yu Lu, Jing Cheng, Fengxiao Bu, Huijun Yuan   +11 more
wiley   +1 more source

Relationships between dipstick proteinuria and risk of hearing impairment among Japanese workers: a prospective cohort study

BMJ Open, 2019
Objectives Hearing impairment is among the most significant health problems, and the number of adults with hearing impairment is increasing worldwide. Therefore, the prevention of hearing impairment is important.
Mitsumasa Umesawa, Toshimi Sairenchi, Yasuo Haruyama, Gen Kobashi, Mikako Hara   +4 more
doaj   +1 more source

Beyond Accessibility: Lifting Perceptual Limitations for Everyone [PDF]

arXiv, 2017
We propose that accessibility research can lay the foundation for technology that can be used to augment the perception of everyone. To show how this can be achieved, we present three case studies of our research in which we demonstrate our approaches for impaired colour vision, situational visual impairments and situational hearing impairment.
arxiv  

STRATEGI KELUARGA DALAM PERAWATAN ANAK DENGAN TUNARUNGU [PDF]

, 2023
: Hearing impairment is a condition where individuals face difficulties in communication. Deaf children encounter various challenges in their growth and development.
Azizah, Valia Rosa
core  

Consequences and Mechanisms of Noise‐Induced Cochlear Synaptopathy and Hidden Hearing Loss, With Focuses on Signal Perception in Noise and Temporal Processing

Advanced Science, EarlyView.
Noise‐induced synaptopathy (NIS) is largely reversible due to self‐repair. NIS and noise‐induced hidden hearing loss are two concepts with similarities and differences. The major hearing deficits in NIHHL are temporal processing disorders. The translation of animal data in NIS studies to humans is hindered by many factors.
Hui Wang, Steven J Aiken, Jian Wang
wiley   +1 more source

Evaluating the Intelligibility Benefits of Neural Speech Enrichment for Listeners with Normal Hearing and Hearing Impairment using the Greek Harvard Corpus [PDF]

arXiv, 2020
In this work we evaluate a neural based speech intelligibility booster based on spectral shaping and dynamic range compression (SSDRC), referred to as WaveNet-based SSDRC (wSSDRC), using a recently designed Greek Harvard-style corpus. The corpus has been developed according to the format of the Harvard/IEEE sentences and offers the opportunity to apply
arxiv  

Hubungan Kebisingan Terhadap Fungsi Pendengaran Pekerja Mesin Pembangkit Listrik Tenaga Diesel Di PLTD Suluttenggo Kota Manado [PDF]

, 2016
: Noise is unwanted sound heard by ears. Damages of ears usually take place on the tympanic membrane or on the ossicles. Initially, there will be loss of hearing to high frequency noises, and it will gradually decrease to the lowest frequency noise. This
Danes, V. R. (Vennetia), Lintong, F. (Fransiska), Timang, R. P. (Ramdan)   +2 more
core  

Long‐Lasting Auditory and Vestibular Recovery Following Gene Replacement Therapy in a Novel Usher Syndrome Type 1c Mouse Model

Advanced Science, EarlyView.
This study shows that gene replacement therapy using the AAV2/Anc80L65 virus can successfully restore hearing and balance in Ush1c knockout mice. The treatment leads to lasting improvements in both auditory and vestibular functions, highlighting its potential as a therapeutic approach for genetic hearing loss and vestibular disorders in humans ...
Weinan Du, Jun Huang, Aizhen Zhang, Fangfang Zhao, Tianwen Chen, Quinn M. McDermott, Tony Zheng, Haibo Wang, Rongli Zhang, Xiaolin Zhang, Jerome Allison, Hong Zhu, Wu Zhou, Qing Yin Zheng   +13 more
wiley   +1 more source

The effect of symmetrical and asymmetrical hearing impairment on the music quality perception [PDF]

, 2015
The purpose of this study was to investigate the effect of symmetrical, asymmetrical and unilateral hearing impairment on music quality perception. Six validated music pieces in the categories of classical music, folk music and pop music were used to ...
Cai, Yuexin Y, Chen, Ling L, Chen, Yuebo Y, Liang, Maojin M, Xiong, Hao H, Yang, Haidi H, Zhang, Xueyuan, Zhao, Fei, Zheng, Yiqing   +8 more
core   +1 more source

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

Advanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao, Tian Shen, Shengda Cao, Ziyi Liu, Wendu Pang, Meixuan Li, Jingjing Liu, Wen Li, Yunhao Wu, Chengcheng Liu, Ming Xia, Xiaolong Fu, Cheng Cheng   +12 more
wiley   +1 more source