Results 21 to 30 of about 2,035,475 (362)
Degeneration of saccular hair cells caused by MITF gene mutation
Neural Development, 2019 Background Waardenburg syndrome (WS) is the consequence of an inherited autosomal dominant mutation which causes the early degeneration of intermediate cells of cochlear stria vascularis (SV) and profound hearing loss.
Yi Du +9 more
doaj +1 more source
WHIS: Hearing impairment simulator based on the gammachirp auditory filterbank [PDF]
IEEE access, 25 July 2023, 2022 A new version of a hearing impairment simulator (WHIS) was implemented based on a revised version of the gammachirp filterbank (GCFB), which incorporates fast frame-based processing, absolute threshold (AT), an audiogram of a hearing-impaired (HI) listener, and a parameter to control the cochlear input-output (IO) function. The parameter referred to as
arxiv +1 more source
Key Genes and Pathways Associated With Inner Ear Malformation in SOX10 p.R109W Mutation Pigs
Frontiers in Molecular Neuroscience, 2018 SRY-box 10 (SOX10) mutation may lead to inner ear deformities. However, its molecular mechanisms on inner ear development are not clear. In this work, the inner ear morphology was investigated at different embryonic stages of the SOX10 mutation miniature
Qing-Qing Hao +8 more
doaj +1 more source
Gene4HL: An Integrated Genetic Database for Hearing Loss
Frontiers in Genetics, 2021 Hearing loss (HL) is one of the most common disabilities in the world. In industrialized countries, HL occurs in 1–2/1,000 newborns, and approximately 60% of HL is caused by genetic factors.
Shasha Huang +57 more
doaj +1 more source
The future of hearing aid technology [PDF]
, 2023 Background. Hearing aid technology has proven successful in the rehabilitation of hearing loss, but its performance is still limited in difficult everyday conditions characterized by noise and reverberation. Objectives. Introduction to the current state of hearing aid technology and presentation of the current state of research and future development.
arxiv +1 more source
A hypothesis study on bionic active noise reduction of auditory organs
Military Medical Research, 2018 Background Noise exposure can lead to hearing loss and multiple system dysfunctions. As various forms of noise exist in our living environments, and our auditory organs are very sensitive to acoustic stimuli, it is a challenge to protect our hearing ...
Qing-Qing Jiang, Ning Yu, Shi-Ming Yang
doaj +1 more source
Frontiers in Pharmacology, 2022 Background: Ecto-5′-nucleotidase (NT5E) encodes the cluster of differentiation 73 (CD73), whose overexpression contributes to the formation of immunosuppressive tumor microenvironment and is related to exacerbated prognosis, increased risk of metastasis ...
Xin-miao Xue +23 more
doaj +1 more source
Cochlear morphology in the developing inner ear of the porcine model of spontaneous deafness
BMC Neuroscience, 2018 Background Auditory function and cochlear morphology have previously been described in a porcine model with spontaneous WS2-like phenotype. In the present study, cochlear histopathology was further investigated in the inner ear of the developing ...
Wei Chen +6 more
doaj +1 more source
BMC Medical Genomics, 2022 Background Mutations in the MYO15A gene are a widely recognized cause of autosomal recessive non-syndromic sensorineural hearing loss (NSHL) globally.
Ying Fu +7 more
doaj +1 more source
A Porcine Congenital Single-Sided Deafness Model, Its Population Statistics and Degenerative Changes
Frontiers in Cell and Developmental Biology, 2021 ObjectiveTo describe and study the population statistics, hearing phenotype, and pathological changes of a porcine congenital single-sided deafness (CSSD) pedigree.MethodsClick auditory brainstem response (ABR), full-frequency ABR, and distortion product
Wei Ren +33 more
doaj +1 more source