Results 21 to 30 of about 139,033 (315)

Hearing Impairment and Retirement [PDF]

Journal of the American Academy of Audiology, 2014
Background:Many factors influence the decision to retire including age, insurance, and pension availability along with physical and mental health. Hearing impairment may be one such factor.Purpose:The purpose of this study was to compare the 15 yr retirement rate among subjects with and without hearing impairment.Research Design:Prospective ...
Mary E, Fischer, Karen J, Cruickshanks, Alex, Pinto, Barbara E K, Klein, Ronald, Klein, Dayna S, Dalton   +5 more
openaire   +2 more sources

Generation of a gene corrected human isogenic iPSC line (CPGHi002-A-1) from a DDOD patient with heterozygous c.1516 C>T mutation in the ATP6V1B2 gene

Stem Cell Research, 2021
Dominant deafness-onychodystrophy (DDOD) syndrome is a rare autosomal dominant disorder caused by mutations in ATP6V1B2 gene. We previously generated an induced pluripotent stem cell (iPSC) line (CPGHi002-A) from a DDOD patient with a heterozygous c.1516
Xue Gao, Shi–Wei Qiu, Wei-Qian Wang, Dong-Yang Kang, Ning Su, Pu Dai, Yong–Yi Yuan   +6 more
doaj   +1 more source

Genetic Analysis of the LOXHD1 Gene in Chinese Patients With Non-Syndromic Hearing Loss

Frontiers in Genetics, 2022
Non-syndromic hearing loss (NSHL) is a common neurosensory disease with an extreme genetic heterogeneity which has been linked to variants in over 120 genes.
Wei-Qian Wang, Wei-Qian Wang, Xue Gao, Xue Gao, Sha-Sha Huang, Dong-Yang Kang, Jin-Cao Xu, Kun Yang, Ming-Yu Han, Xin Zhang, Su-Yan Yang, Yong-Yi Yuan, Pu Dai   +12 more
doaj   +1 more source

Automatic Recognition of Auditory Brainstem Response Characteristic Waveform Based on Bidirectional Long Short-Term Memory

Frontiers in Medicine, 2021
Background: Auditory brainstem response (ABR) testing is an invasive electrophysiological auditory function test. Its waveforms and threshold can reflect auditory functional changes in the auditory centers in the brainstem and are widely used in the ...
Cheng Chen, Li Zhan, Xiaoxin Pan, Zhiliang Wang, Xiaoyu Guo, Handai Qin, Fen Xiong, Wei Shi, Min Shi, Fei Ji, Qiuju Wang, Ning Yu, Ruoxiu Xiao, Ruoxiu Xiao   +13 more
doaj   +1 more source

Degeneration of saccular hair cells caused by MITF gene mutation

Neural Development, 2019
Background Waardenburg syndrome (WS) is the consequence of an inherited autosomal dominant mutation which causes the early degeneration of intermediate cells of cochlear stria vascularis (SV) and profound hearing loss.
Yi Du, Li-li Ren, Qing-qing Jiang, Xing-jian Liu, Fei Ji, Yue Zhang, Shuo-long Yuan, Zi-Ming Wu, Wei-Wei Guo, Shi-Ming Yang   +9 more
doaj   +1 more source

Key Genes and Pathways Associated With Inner Ear Malformation in SOX10 p.R109W Mutation Pigs

Frontiers in Molecular Neuroscience, 2018
SRY-box 10 (SOX10) mutation may lead to inner ear deformities. However, its molecular mechanisms on inner ear development are not clear. In this work, the inner ear morphology was investigated at different embryonic stages of the SOX10 mutation miniature
Qing-Qing Hao, Liang Li, Wei Chen, Qing-Qing Jiang, Fei Ji, Wei Sun, Hong Wei, Wei-Wei Guo, Shi-Ming Yang   +8 more
doaj   +1 more source

A hypothesis study on bionic active noise reduction of auditory organs

Military Medical Research, 2018
Background Noise exposure can lead to hearing loss and multiple system dysfunctions. As various forms of noise exist in our living environments, and our auditory organs are very sensitive to acoustic stimuli, it is a challenge to protect our hearing ...
Qing-Qing Jiang, Ning Yu, Shi-Ming Yang
doaj   +1 more source

Generation of a human induced pluripotent stem cell line (CPGHi001-A) from a hearing loss patient with the TMC1 p.M418K mutation

Stem Cell Research, 2020
By using a nonintegrating plasmid delivery system, we generated induced pluripotent stem cells (iPSCs) from the urine cells of a male patient from the family carrying the TMC1 p.M418K mutation. This mutation is homologous to that in Beethoven mice, which
Hongyang Wang, Kaiwen Wu, Jing Guan, Qiuju Wang   +3 more
doaj   +1 more source

NT5E upregulation in head and neck squamous cell carcinoma: A novel biomarker on cancer-associated fibroblasts for predicting immunosuppressive tumor microenvironment

Frontiers in Immunology, 2022
Despite tremendous progress made in the diagnosis and managements, head and neck squamous cell carcinoma (HNSC) remains a global medical dilemma with dismal clinical prognosis and high mortality.
Xue-min Chen, Xue-min Chen, Yu-yang Liu, Yu-yang Liu, Bing-yan Tao, Bing-yan Tao, Xin-miao Xue, Xin-miao Xue, Xin-xin Zhang, Lin-lin Wang, Hui Zhong, Hui Zhong, Jun Zhang, Shi-ming Yang, Qing-qing Jiang   +14 more
doaj   +1 more source

Gender-specific associations of vision and hearing impairments with adverse health outcomes in older Japanese: a population-based cohort study. [PDF]

, 2009
BACKGROUND: Several epidemiological studies have shown that self-reported vision and hearing impairments are associated with adverse health outcomes (AHOs) in older populations; however, few studies have used objective sensory measurements or ...
Makiko Nakano, Tomonori Okamura, Satoko Iwasawa, Saito, Hideyuki, Ai Milojevic, Kikuchi, Yuriko, Milojevic, Ai, Okamura, Tomonori, Iwasawa, Satoko, Toru Takebayashi, Nakano, Makiko, Kunio Mizutari, Hideyuki Saito, Nishiwaki, Yuji, Takehiro Michikawa, Yuriko Kikuchi, Susumu Ishida, Takebayashi, Toru, Asakura, Keiko, Mizutari, Kunio, Yuji Nishiwaki, Ishida, Susumu, Keiko Asakura, Michikawa, Takehiro   +23 more
core   +1 more source