Co-transduction of dual-adeno-associated virus vectors in the neonatal and adult mouse utricles
Adeno-associated virus (AAV)-mediated gene transfer is an efficient method of gene over-expression in the vestibular end organs. However, AAV has limited usefulness for delivering a large gene, or multiple genes, due to its small packaging capacity (<
Zhong-Rui Chen +19 more
doaj +1 more source
Cochlear resident macrophage mediates development of ribbon synapses via CX3CR1/CX3CL1 axis
Cochlear ribbon synapses formed between spiral ganglion neurons and inner hair cells in postnatal mice must undergo significant morphological and functional development to reach auditory maturation.
Xinyu Song +19 more
doaj +1 more source
A review on the impacts of COVID-19 on the auditory system: Implications for public health promotion research [PDF]
Background: Currently, there are few studies on the relationship between COVID-19 and the auditory system. In the current study, a review of the studies conducted in the fields of etiopathology, clinical manifestations, research, and treatment of hearing
Samin Shibafar, Fatemeh Jafarlou
doaj +1 more source
This review aims to draw attention to the multiple ipsilateral otic capsule dehiscences (OCDs), which may cause therapeutic failure in operated patients.
Eugen C. Ionescu +14 more
doaj +1 more source
The interference of tinnitus on sound localization was related to the type of stimulus
Spatial processing is a major cognitive function of hearing. Sound source localization is an intuitive evaluation of spatial hearing. Current evidence of the effect of tinnitus on sound source localization remains limited.
Yue Long +6 more
doaj +1 more source
Effect of tinnitus on sound localization ability in patients with normal hearing
Objectives: To determine whether tinnitus negatively impacts the accuracy of sound source localization in participants with normal hearing. Methods: Seventy-five participants with tinnitus and 74 without tinnitus were enrolled in this study. The accuracy
Yue Long +4 more
doaj +1 more source
Pure Tone Audiometry Findings before and after Radiotherapy in Head and Neck Cancer Patients: A Hospital-based Prospective Interventional Study [PDF]
Introduction: Radiotherapy is still the major treatment modality for Head and Neck malignancies preferred by patients as well as surgeons. Temporal bone and brain stem are mostly included in the portals.
MD Taher Ahmed Mazumder +3 more
doaj +1 more source
Isolated Sensorineural Hearing Loss as the Sole Manifestation of Granulomatosis with Polyangiitis. [PDF]
Arango A, Mumtaz S, Abril A.
europepmc +3 more sources
Delivering Therapeutics to the Cochlea: The Importance of the Patient’s Perspective
Hearing loss represents a major sensory impairment in humans with a strong impact on quality of life. The current standard of care for chronic sensorineural hearing loss is limited to hearing aids and implantable devices like cochlear implants ...
Marie-Josée Duran, Ralph Holme
doaj +1 more source
Hearing Loss in Adults - Silent Epidemic
Introduction: Hearing loss affects 15% of Poles, i.e. more than 5.7 million people. Despite this, it is still underdiagnosed and insufficiently often treated.
Inga Magda +6 more
doaj +1 more source

