Leveraging underrepresented population data improves interpretation of genetic variants associated with hearing loss [PDF]
Scientific ReportsHearing loss is genetically heterogeneous, with over 121 implicated genes. Minor allele frequency (MAF) data from population databases greatly aid variant interpretation; however, these databases are predominantly based on individuals of European ...
Sun Young Joo +6 more
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Co-transduction of dual-adeno-associated virus vectors in the neonatal and adult mouse utricles
Frontiers in Molecular Neuroscience, 2022 Adeno-associated virus (AAV)-mediated gene transfer is an efficient method of gene over-expression in the vestibular end organs. However, AAV has limited usefulness for delivering a large gene, or multiple genes, due to its small packaging capacity (<
Zhong-Rui Chen +19 more
doaj +1 more source
Cochlear resident macrophage mediates development of ribbon synapses via CX3CR1/CX3CL1 axis
Frontiers in Molecular Neuroscience, 2022 Cochlear ribbon synapses formed between spiral ganglion neurons and inner hair cells in postnatal mice must undergo significant morphological and functional development to reach auditory maturation.
Xinyu Song +19 more
doaj +1 more source
A review on the impacts of COVID-19 on the auditory system: Implications for public health promotion research [PDF]
Health Promotion Perspectives, 2023 Background: Currently, there are few studies on the relationship between COVID-19 and the auditory system. In the current study, a review of the studies conducted in the fields of etiopathology, clinical manifestations, research, and treatment of hearing
Samin Shibafar, Fatemeh Jafarlou
doaj +1 more source
Frontiers in Neurology, 2023 This review aims to draw attention to the multiple ipsilateral otic capsule dehiscences (OCDs), which may cause therapeutic failure in operated patients.
Eugen C. Ionescu +14 more
doaj +1 more source
The interference of tinnitus on sound localization was related to the type of stimulus
Frontiers in Neuroscience, 2023 Spatial processing is a major cognitive function of hearing. Sound source localization is an intuitive evaluation of spatial hearing. Current evidence of the effect of tinnitus on sound source localization remains limited.
Yue Long +6 more
doaj +1 more source
Effect of tinnitus on sound localization ability in patients with normal hearing
Brazilian Journal of Otorhinolaryngology, 2023 Objectives: To determine whether tinnitus negatively impacts the accuracy of sound source localization in participants with normal hearing. Methods: Seventy-five participants with tinnitus and 74 without tinnitus were enrolled in this study. The accuracy
Yue Long +4 more
doaj +1 more source
Pure Tone Audiometry Findings before and after Radiotherapy in Head and Neck Cancer Patients: A Hospital-based Prospective Interventional Study [PDF]
Journal of Clinical and Diagnostic Research, 2023 Introduction: Radiotherapy is still the major treatment modality for Head and Neck malignancies preferred by patients as well as surgeons. Temporal bone and brain stem are mostly included in the portals.
MD Taher Ahmed Mazumder +3 more
doaj +1 more source
Recovery from repeated sudden hearing loss in a patient with Takayasu’s arteritis treated with hyperbaric oxygen therapy: the first report in the literature [PDF]
, 2017 Hearing loss has been rarely reported in Takayasu's arteritis, presents as sudden sensorineural hearing loss and usually responds well to corticosteroid therapy.
ALTISSIMI, Giancarlo +8 more
core +7 more sources
Hearing in young adults, part I: the effects of attitudes and beliefs toward noise, hearing loss and hearing protector devices [PDF]
, 2015 There is great concern regarding the development of noise-induced hearing loss (NIHL) in youth caused by high sound levels during various leisure activities.
Dhooge, Ingeborg +2 more
core +4 more sources