Scientific research with animals in the UK is regulated by the Animals (Scientific Procedures) Act 1986 with the National Centre for the Replacement, Refinement and Reduction of Animals in Research providing support for best practice and facilitating development of new approach methodologies.
Ewan St. John Smith +6 more
wiley +1 more source
Clinical implementation and evaluation of a patient-specific surface-guided clearance mapping system for collision avoidance and noncoplanar beam planning. [PDF]
Wang S +10 more
europepmc +1 more source
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
Sheep Horn Development Revealed by Multi‐Tissue and Cross‐Species Transcriptomic Analysis
Multi‐tissue and cross‐species transcriptomics with allele‐specific expression show sheep horns are a composite organ integrating epidermal and osteogenic programs. Conserved horn gene modules and cis‐regulatory variation fine‐tune expression networks underlying horn development and size (small scurs vs. large spiral horns).
Hao Li +10 more
wiley +1 more source
Development of an Artificial Intelligence Web Application for Predicting Chemotherapy-Induced Neutropenia in Patients With Non-Small Cell Lung Cancer: A Prospective Study. [PDF]
Zhang J +11 more
europepmc +1 more source
Objective To develop, externally validate, and simplify a machine learning model to predict remission between 6 and 24 months in patients with rheumatoid arthritis (RA) initiating tumor necrosis factor inhibitors, JAK inhibitors, interleukin‐6 inhibitors, abatacept, or rituximab using data from 11 international registries in the JAK‐pot collaboration ...
Zubeyir Salis +22 more
wiley +1 more source
Machine Learning Model for Predicting Postoperative Complications in Pediatric Simple Congenital Heart Disease with Right Vertical Infra-Axillary Incision. [PDF]
Shi C +6 more
europepmc +1 more source
Expert Perspectives: Defining and managing progressive pulmonary fibrosis in systemic sclerosis
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Devis Benfaremo +7 more
wiley +1 more source
Can Artificial Intelligence Interpret Pulmonary Function Tests and Predict Prolonged Air Leaks After Lung Resection. [PDF]
Zahra O +8 more
europepmc +1 more source

