Sheep Horn Development Revealed by Multi‐Tissue and Cross‐Species Transcriptomic Analysis
Multi‐tissue and cross‐species transcriptomics with allele‐specific expression show sheep horns are a composite organ integrating epidermal and osteogenic programs. Conserved horn gene modules and cis‐regulatory variation fine‐tune expression networks underlying horn development and size (small scurs vs. large spiral horns).
Hao Li +10 more
wiley +1 more source
Cardiopulmonary exercise testing before lung resection surgery: still indicated? Evaluating predictive utility using machine learning. [PDF]
Filakovszky Á +7 more
europepmc +1 more source
Three Safety Devices for the Heart-Lung Machine
F, OLMSTED, W J, KOLFF, D B, EFFLER
openaire +2 more sources
Objective To develop, externally validate, and simplify a machine learning model to predict remission between 6 and 24 months in patients with rheumatoid arthritis (RA) initiating tumor necrosis factor inhibitors, JAK inhibitors, interleukin‐6 inhibitors, abatacept, or rituximab using data from 11 international registries in the JAK‐pot collaboration ...
Zubeyir Salis +22 more
wiley +1 more source
Time as a Therapeutic Ally: The Promise of Long-Term Solid Organ and Tissue Perfusion. [PDF]
Huwyler F +14 more
europepmc +1 more source
Expert Perspectives: Defining and Managing Progressive Pulmonary Fibrosis in Systemic Sclerosis
Systemic sclerosis–associated interstitial lung disease (SSc‐ILD) is one of the leading causes of morbidity and mortality in SSc, affecting up to three‐quarters of patients. The disease course is highly heterogeneous, ranging from indolent, nonprogressive forms to rapidly progressive pulmonary fibrosis (PPF).
Devis Benfaremo +7 more
wiley +1 more source
Identification and Validation of an Explainable Predictive Model For Heart Failure in Patients With Hypertension. [PDF]
Han J +12 more
europepmc +1 more source
Objective Rheumatoid arthritis (RA) often involves extra‐articular complications, including interstitial lung disease (ILD) and/or pulmonary nodules. Transcriptomic profiling of lung tissue provides the opportunity to directly assess cell‐specific gene expression and corresponding pathway activation in different types of rheumatoid lung disease ...
Tracy Tabib +8 more
wiley +1 more source
Integrated cross-organ transcriptomic analysis uncovers conserved gene signatures predictive of allograft rejection. [PDF]
Poorvi HC, Vinod PK.
europepmc +1 more source
From classroom to clinic: Evaluating the educational utility of two Thiel embalming methods
Abstract Over three decades since its introduction, the Thiel embalming method remains a widely used and praised technique in anatomical education and clinical training. This study compared for the first time the Thiel original protocol (TO) and a Modified version (TM) across user groups—undergraduate medical students, student demonstrators in anatomy,
Veronica Antipova +3 more
wiley +1 more source

