Results 131 to 140 of about 57,409 (264)

Cardiopulmonary exercise testing before lung resection surgery: still indicated? Evaluating predictive utility using machine learning. [PDF]

Thorax
Filakovszky Á, Brat K, Tschoellitsch T, Bartos S, Mazur A, Meier J, Olson L, Cundrle I.   +7 more
europepmc   +1 more source

Design, Control, and Clinical Applications of Magnetic Actuation Systems: Challenges and Opportunities

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo, Lidong Yang, Tiantian Xu, Dong Sun   +3 more
wiley   +1 more source

Time as a Therapeutic Ally: The Promise of Long-Term Solid Organ and Tissue Perfusion. [PDF]

Transpl Int
Huwyler F, Pfister M, Phuyal D, Dean YE, Mittendorfer M, Saemann L, Rasel H, Stoerzer S, Binz J, Tabatabaei B, Szabo G, Lindstedt S, Bassiri Gharb B, Tibbitt MW, Clavien PA.   +14 more
europepmc   +1 more source

One‐step generation of heritable mitochondrial DNA multiplex‐engineered rats using DddA‐derived cytosine base editor

Animal Models and Experimental Medicine, EarlyView.
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang, Keru Li, Lei Tan, Wei Chen, Shan Gao, Chenyang Liu, Shuo Pan, Jiayue He, Ning Liu, Gefan Wan, Wei Dong, Weining Kong, Bin Shen, Xiaolong Qi, Yuanwu Ma   +14 more
wiley   +1 more source

Integrated cross-organ transcriptomic analysis uncovers conserved gene signatures predictive of allograft rejection. [PDF]

PLoS One
Poorvi HC, Vinod PK.
europepmc   +1 more source

THE PREPARATION, ASSEMBLY, AND OPERATION OF A HEART-LUNG MACHINE

The Journal of Thoracic and Cardiovascular Surgery, 1962
R G, STOFER, R R, LOWER, N E, SHUMWAY
openaire   +2 more sources

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

Stem cell–based therapies for type 1 diabetes: Progress in differentiation, clinical translation, and immune protection

Animal Models and Experimental Medicine, EarlyView.
Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley   +1 more source

Surgical technique of donation after circulatory death heart procurement using direct procurement and hypothermic oxygenated perfusion preservation. [PDF]

JHLT Open
Vandendriessche K, Brouckaert J, Van de Voorde K, Gaublomme F, Degezelle K, Van Cleemput J, Wallinder A, Rega F.   +7 more
europepmc   +1 more source

Three Safety Devices for the Heart-Lung Machine

Cleveland Clinic Journal of Medicine, 1958
F, OLMSTED, W J, KOLFF, D B, EFFLER
openaire   +2 more sources