Results 131 to 140 of about 3,864,619 (301)

Dual‐Targeting Biomimetic Nanozymes Loaded Microneedle Patch Promotes Scarless Wound Healing Through Anti‐Inflammatory and Anti‐Fibrotic Effects

Advanced Science, EarlyView.
This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang, Jinwei Li, Shan Hua, Shengming Wu, Chenlong He, Yuan Zhu, Ming Yin, Han Zhou, Huawei Liu, Chika Hasegawa, Jun Lyu, Keyue Xiao, Hua Jiang, Yilong Wang, Yuxin Qian   +14 more
wiley   +1 more source

An effective ECOLASSO with black widow optimization for feature selection and stagewise adaptive learning rate for disease prediction

Discover Artificial Intelligence
Machine learning techniques are utilized for early detection of diseases, which can significantly enhance probabilities of positive treatment and existence.
G. Vijaya, G. Sathish Kumar, G. Uma Maheshwari, M. Karthiga, S. Hemkiran, Seyed Jalaleddin Mousavirad, Ghanshyam G. Tejani   +6 more
doaj   +1 more source

Intelligent Prediction of Human Health Risks Based on Medical History: A Review

Al-Rafidain Journal of Computer Sciences and Mathematics
The main access to modern healthcare using artificial technologies is related to the medical topic and prediction of risks to human health. Enhance patient medical care using intelligent prediction models such as machine learning, like gradient boosting
Mais Irreem A kamal, Fawziya M. Ramo
doaj   +1 more source

Klotho‐Derived Peptide 1 Protects against Acute Kidney Injury by Directly Targeting Mitochondrial ATAD3A

Advanced Science, EarlyView.
This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang, Shihui Lin, Tianyu Wu, Zhixin Zhang, Hong Zhou, Xue Hong, Youhua Liu   +6 more
wiley   +1 more source

Proposing a Formal Approach for Verification of Heart-Lung Machine

, 2015
Introduction: error occurrence in computer systems, can lead to irreparable damage, especially those used in medical systems. As a result, verification of such systems is important.
Rafeh, Reza
core   +1 more source

Establishing a Ventilator-Heart Lung Machine Communication Bridge to Mitigate Errors when Weaning from Bypass. [PDF]

J Extra Corpor Technol, 2019
Rance G, Arney D, Srey R, Goldman JM, Zenati MA.   +4 more
europepmc   +1 more source

Sterilizing procedures for heart-lung machines [PDF]

Journal of Clinical Pathology, 1963
openaire   +2 more sources

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

Advanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu, Ling Li, Sachin S. Surwase, Xin Ming M. Zhou, Hongtao Qian, Joel C. Sunshine, Florin M. Selaru, Jordan J. Green   +7 more
wiley   +1 more source

Assessing and managing frailty in advanced heart failure: An International Society for Heart and Lung Transplantation consensus statement

Frailty is increasingly recognized as a salient condition in patients with heart failure (HF) as previous studies have determined that frailty is highly prevalent and prognostically significant, particularly in those with advanced HF.
Lindenfeld, Joann, Afilalo, Jonathan, Kobashigawa, Jon, Uchmanowicz, Izabella, De Geest, S, Reeves, Gordon R., Gorodeski, EZ, Afilalo, J, McDonagh, J, Joyce, Emer, Mcdonagh, Julee, Beerli, N, Gorodeski, Eiran Z., Jha, Sunita R., Macdonald, Peter, Mauthner, Oliver, Bellumkonda, Lavanya, Denfeld, QE, Maurer, Mathew S., Beerli, Nadine, Jha, SR, Jaarsma, T, Uchmanowicz, I, Lindenfeld, J, Reeves, GR, Fung, E, Maurer, MS, Fung, Erik, Jaarsma, Tiny, Dickson, Victoria Vaughan, Dickson, VV, De Geest, Sabina, Mauthner, O, Bellumkonda, L, Macdonald, P, Kobashigawa, J, Denfeld, Quin E., Joyce, E, Lindenfeld, Jo Ann   +38 more
core   +1 more source

WTAP Transcriptional Suppression by KLF9 Drives Osteoclastogenesis via M6A‐Mediated Regulation of CSF1R Signaling in Estrogen‐Deficient Osteoporosis

Advanced Science, EarlyView.
Scheme of the KLF9/WTAP/YTHDF2/m6A/CSF1R regulatory axis in osteoclastogenesis and estrogen‐deficient osteoporosis. WTAP‐mediated m6A modification of Csf1r mRNA governs osteoclastogenesis via a YTHDF2‐mediated pathway. Pathological upregulation of KLF9 drives Wtap transcription, leading to increased m6A deposition on the 3’‐UTR of Csf1r mRNA.
Chen Shen, Xin Liu, Gaoran Ge, Li Xu, Ziyu Zhang, Chang Lv, Hao Xu, Wenhao Li, Yi Qin, Qifeng Sheng, Qihan Wang, Hongxia Li, Jun Zhou, Huilin Yang, Dechun Geng   +14 more
wiley   +1 more source