Results 51 to 60 of about 192,679 (274)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Improving the Segmentation of Anatomical Structures in Chest Radiographs using U-Net with an ImageNet Pre-trained Encoder

, 2018
Accurate segmentation of anatomical structures in chest radiographs is essential for many computer-aided diagnosis tasks. In this paper we investigate the latest fully-convolutional architectures for the task of multi-class segmentation of the lungs ...
AA Novikov, B Ginneken Van, H Greenspan, J Shiraishi, LC Chen, O Ronneberger, S Hwang, SSM Salehi, W Yang   +8 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

John H. Gibbon, Jr., M.D.: surgical innovator, pioneer, and inspiration. [PDF]

, 2011
Throughout history there have been many discoveries that have changed the world, including Albert Einstein’s theory of relativity, Alexander Graham Bell’s telephone, and Jack Kilby and Robert Noyce’s microchip.
Bloom, B.S., Jordan P., Cohn, MD, Herbert E., Maxwell, IV, MD, Pinckney J., Yeo, MD, Charles J.   +3 more
core   +1 more source

Lung protection in cardio-pulmonary bypass [PDF]

, 2017
Since the invention of the heart-lung machine paediatric cardiac surgery developed rapidly. For correction of complex cardiac malformations the application of a cardio-pulmonary bypass (CPB) has become indispensable but possible negative effects of this ...
Bahramsoltani, M., Dahnert, I., Dhein, S., Greimann, W., Salameh, A., Vollroth, M.   +5 more
core   +1 more source

Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas, Connor A. Law, Joan A. Casey, Thomas Mosley, Rebecca F. Gottesman, Ramon Diaz‐Arrastia, Holly Elser, Andrea L. C. Schneider   +7 more
wiley   +1 more source

Generative AI Respiratory and Cardiac Sound Separation Using Variational Autoencoders (VAEs)

Computer Sciences & Mathematics Forum
The separation of respiratory and cardiac sounds is a significant challenge in biomedical signal processing due to their overlapping frequency and time characteristics.
Arshad Jamal, R. Kanesaraj Ramasamy, Junaidi Abdullah   +2 more
doaj   +1 more source

Accuracy of trans-thoracic echocardiography as a pericardial diseases diagnostic tool

Ibom Medical Journal, 2006
Summary A prospective comparison of pre-operative trans-thoracic echocardiographic findings with intra-operative findings of 17 patients operated on for pericardial diseases showed excellent correlation for pericardial calcification and adhesion, and ...
Ekpe EE, Anyanwu CH
doaj   +1 more source

The Role of Perfusionists during the COVID-19 Pandemic and Clinical Laboratory Technologists: Comparison of Training Systems in Japan and the United States

Korean Journal of Clinical Laboratory Science, 2022
In 2022, Korea reported a total of 224 perfusionists, employing nurses or clinical laboratory technologists (also known as medical technologists) to provide hospital self-education or reliable education.
Dong-Ok Aum, Dae Jin Kim, Dae Eun Kim, Myong Soo Kim, Bon-Kyeong Koo   +4 more
doaj   +1 more source

Sliding to predict: vision-based beating heart motion estimation by modeling temporal interactions [PDF]

, 2018
Purpose: Technical advancements have been part of modern medical solutions as they promote better surgical alternatives that serve to the benefit of patients.
Alsaleh, Samar M., Avilés Rivero, Angélica, Casals Gelpi, Alicia   +2 more
core   +1 more source