Results 31 to 40 of about 3,864,619 (301)

Clinical characteristics of hemodynamics and laboratory parameters of recipients during orthotopic heart transplantation

open access: yesУкраїнський журнал клінічної хірургії
Objective. To study the clinical and laboratory characteristics of recipients during orthotopic heart transplantation according to intraoperative monitoring. Materials and methods.
M. M. Goncharenko
doaj   +1 more source

Non-Invasive Assessment of Lung Water Content Using Chest Patch RF Sensors: A Computer Study Using NIH Patients CT Scan Database and AI Classification Algorithms

open access: yesIEEE Access, 2023
Chronic heart failure, pulmonary hypertension, acute respiratory distress syndrome (ARDS), coronavirus disease (COVID), and kidney failure are leading causes of death in the U.S. and across the globe.
Christopher Leong   +3 more
doaj   +1 more source

The role of stromal cells in the mouse model of respiratory syncytial virus infection [PDF]

open access: yes, 2016
Respiratory Syncytial Virus (RSV) is the single most important cause of acute lower respiratory tract infections in infants. Most children are infected with RSV by the age of two, and the majority of them suffer only a simple cold. However, 1- 3% develop
Kausar, Fahima
core   +1 more source

Myocardial slices as an in vitro platform to study cardiac disease [PDF]

open access: yes, 2021
In vitro models are the pillars of fundamental research and drug discovery, offering reductionist methods to better understand cellular responses in isolation.
Bardi, Ifigeneia
core   +1 more source

Leveraging Machine Perfusion to Ameliorate Geographic Disparities in Organ Allocation

open access: yesVoices in Bioethics, 2021
Photo by Robina Weermeijer on Unsplash INTRODUCTION  Geographic inequities in access to donor lungs have persisted since the first successful lung transplant in 1983.[1] With unanswered questions regarding organ preservation and transport in the ...
Derek Soled, Cray Noah
doaj   +1 more source

Investigating the Role of COX-1 and COX-2 in Toll-Like Receptor Responses [PDF]

open access: yes, 2015
COX is the rate-limiting enzyme in the conversion of arachidonic acid to the prostanoids. It is present in humans as two isoforms, COX-1 and COX-2. COX-1 is constitutively expressed and involved in homeostatic functions, while COX-2 expression is mostly ...
Wright, William
core   +1 more source

Measuring Exhaled Propofol in an Ex Vivo Lung Model with Low-Cost Metal Oxide Gas Sensors

open access: yesProceedings
Herein, commercially available MOS gas sensors running in temperature cycling operations are studied for the online monitoring of propofol in an ex vivo ventilation and perfusion lung model.
Christian Bur   +6 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Primary graft dysfunction prevention strategies in the perioperative period

open access: yesJHLT Open
Background: Primary graft dysfunction (PGD) remains a leading cause of early morbidity and mortality after heart and lung transplantation. It results from a multifactorial process involving ischemia–reperfusion injury, inflammatory and immune responses ...
Jérémie Guillemin, MD   +5 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

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