Results 21 to 30 of about 56,070 (265)

Primary graft dysfunction prevention strategies in the perioperative period

JHLT Open
Background: Primary graft dysfunction (PGD) remains a leading cause of early morbidity and mortality after heart and lung transplantation. It results from a multifactorial process involving ischemia–reperfusion injury, inflammatory and immune responses ...
Jérémie Guillemin, MD, Michael Cutrone, DO, Suraj Yalamuri, MD, Monica Arndt, MD, Adrien Bouglé, MD, PhD, Sharon L. McCartney, MD, FASE   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Lung disease recognition methods using audio-based analysis with machine learning

Heliyon
The use of computer-based automated approaches and improvements in lung sound recording techniques have made lung sound-based diagnostics even better and devoid of subjectivity errors. Using a computer to evaluate lung sound features more thoroughly with
Ahmad H. Sabry, Omar I. Dallal Bashi, N.H. Nik Ali, Yasir Mahmood Al Kubaisi   +3 more
doaj   +1 more source

Fractional-Order Control of a Nonlinear Time-Delay System: Case Study in Oxygen Regulation in the Heart-Lung Machine

Journal of Control Science and Engineering, 2012
A fractional-order controller will be proposed to regulate the inlet oxygen into the heart-lung machine. An analytical approach will be explained to satisfy some requirements together with practical implementation of some restrictions for the first time.
S. J. Sadati, A. Ranjbar Noei, R. Ghaderi   +2 more
doaj   +1 more source

VENTRICLE ASSIST DEVICE: PAST, PRESENT, AND FUTURE NONPULSATILE PUMPS

Вестник трансплантологии и искусственных органов, 2009
The article briefly describes the history of the non-pulsating type blood pumps for ventricular assist circulation and heart-lung machine. Disclosed the main advantages of these pumps before pulsating type, especially for implantable systems development.
G. Р. Itkin
doaj   +1 more source

dr Jovan Mijušković, precursor of cardiac surgery in Serbia [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2020
The beginnings of cardiac surgery in Serbia date back to the aftermath of World War II, when the first “closed heart surgery” was performed in Belgrade.
Velimirović Dušan
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

B-line quantification: comparing learners novice to lung ultrasound assisted by machine artificial intelligence technology to expert review

The Ultrasound Journal, 2021
Background The goal of this study was to assess the ability of machine artificial intelligence (AI) to quantitatively assess lung ultrasound (LUS) B-line presence using images obtained by learners novice to LUS in patients with acute heart failure (AHF),
Frances M. Russell, Robert R. Ehrman, Allen Barton, Elisa Sarmiento, Jakob E. Ottenhoff, Benjamin K. Nti   +5 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Enhancement of Chest X-Ray Images to Improve Screening Accuracy Rate Using Iterated Function System and Multilayer Fractional-Order Machine Learning Classifier

IEEE Photonics Journal, 2020
Chest X-ray (CXR) images are usually used to identify the causes of patients’ symptoms, including the classes of lung or heart disorders. In visualization examination, CXR imaging in anterior–posterior (A–P) views is a preliminary ...
Chia-Hung Lin, Jian-Xing Wu, Chien-Ming Li, Pi-Yun Chen, Neng-Sheng Pai, Ying-Che Kuo   +5 more
doaj   +1 more source