Results 21 to 30 of about 57,851 (263)

Measuring Exhaled Propofol in an Ex Vivo Lung Model with Low-Cost Metal Oxide Gas Sensors

Proceedings
Herein, commercially available MOS gas sensors running in temperature cycling operations are studied for the online monitoring of propofol in an ex vivo ventilation and perfusion lung model.
Christian Bur, Ksenia Karst, Andreas Schütze, Felix Maurer, Stefan Radermacher, Klaus Hoffmann, Sascha Kreuer   +6 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Primary graft dysfunction prevention strategies in the perioperative period

JHLT Open
Background: Primary graft dysfunction (PGD) remains a leading cause of early morbidity and mortality after heart and lung transplantation. It results from a multifactorial process involving ischemia–reperfusion injury, inflammatory and immune responses ...
Jérémie Guillemin, MD, Michael Cutrone, DO, Suraj Yalamuri, MD, Monica Arndt, MD, Adrien Bouglé, MD, PhD, Sharon L. McCartney, MD, FASE   +5 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Fractional-Order Control of a Nonlinear Time-Delay System: Case Study in Oxygen Regulation in the Heart-Lung Machine

Journal of Control Science and Engineering, 2012
A fractional-order controller will be proposed to regulate the inlet oxygen into the heart-lung machine. An analytical approach will be explained to satisfy some requirements together with practical implementation of some restrictions for the first time.
S. J. Sadati, A. Ranjbar Noei, R. Ghaderi   +2 more
doaj   +1 more source

VENTRICLE ASSIST DEVICE: PAST, PRESENT, AND FUTURE NONPULSATILE PUMPS

Вестник трансплантологии и искусственных органов, 2009
The article briefly describes the history of the non-pulsating type blood pumps for ventricular assist circulation and heart-lung machine. Disclosed the main advantages of these pumps before pulsating type, especially for implantable systems development.
G. Р. Itkin
doaj   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

The history of cardiopulmonary bypass and the evolution of pneuma in cardiopulmonary medicine

Archives of Medical Science: Atherosclerotic Diseases
Cardiopulmonary bypass (CPB) is one of the most groundbreaking medical innovations in history, enabling safe and effective heart surgery by temporarily replacing the function of the heart and lungs.
Vasileios Leivaditis, Georgios Mavroudes, Hermann Braun Lambur, Nikolaos Baikoussis, Elias Liolis, Konstantinos Tasios, Levan Tchabashvili, George Theofanis, Andreas Antzoulas, Dimitrios Litsas, Panagiotis Dimitrios Papadopoulos, Konstantinos Nikolakopoulos, Manfred Dahm, Spyros Papadoulas, Francesk Mulita   +14 more
doaj   +1 more source