Results 81 to 90 of about 3,864,619 (301)

Heart or heart-lung transplantation for patients with congenital heart disease in England [PDF]

open access: yes, 2018
BACKGROUND: Increased longevity in patients with congenital heart disease (CHD) is associated with late complications, mainly heart failure, which may not be amenable to redo surgery and become refractory to medical therapy and so, trigger referral for ...
Muthiah, Kavitha   +9 more
core   +1 more source

Current Collector Engineering for New Efficient Bioresorbable Sodium‐Ion Batteries

open access: yesAdvanced Science, EarlyView.
A bioresorbable Na‐ion battery is proposed with Mo or Mg thin‐film current collectors for temporary implants. Mo‐based batteries exhibit superior electrochemical performance and stable cycling compared with Mg counterparts. XPS was used to investigate the Mo/Mg surface oxidation.
Bincy Lathakumary Vijayan   +15 more
wiley   +1 more source

Machine Learning for 1-Year Mortality Prediction in Lung Transplant Recipients: ISHLT Registry

open access: yesTransplant International
Optimizing lung transplant candidate selection is crucial for maximizing resource efficiency and improving patient outcomes. Using data from the International Society for Heart and Lung Transplantation (ISHLT) registry (29,364 patients), we developed a ...
Hye Ju Yeo   +9 more
doaj   +1 more source

Dysfunction of contractile proteins in hypertrophic cardiomyopathy [PDF]

open access: yes, 2012
The contractility of human heart samples from patients diagnosed with hypertrophic cardiomyopathy were studied using a quantitative in vitro motility assay.
Bayliss, Christopher Richard
core   +1 more source

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

open access: yesAdvanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai   +9 more
wiley   +1 more source

Relationship of macrophage function and phenotype in COPD [PDF]

open access: yes, 2018
Chronic obstructive pulmonary disease (COPD) is associated with elevated inflammatory signals, protease activity and reduced clearance of pathogens.
Tilman, Jessica Dorsie
core   +1 more source

Inhalable ROS‐Responsive Nanospray Activates PPAR‐γ to Restore Macrophage Mitochondrial Homeostasis and Attenuate Radiation‐Induced Lung Injury

open access: yesAdvanced Science, EarlyView.
A nebulized nanoassembly alleviates radiation‐induced lung injury by reprogramming macrophages through coordinated ROS scavenging, NAD+ replenishment, and PPAR‐γ activation. Redox balance, mitochondrial homeostasis, and immune regulation are restored, revealing a microenvironment‐centered strategy for localized radioprotection.
Mingquan Gao   +11 more
wiley   +1 more source

scDOT: optimal transport for mapping senescent cells in spatial transcriptomics

open access: yesGenome Biology
The low resolution of spatial transcriptomics data necessitates additional information for optimal use. We developed scDOT, which combines spatial transcriptomics and single cell RNA sequencing to improve the ability to reconstruct single cell resolved ...
Nam D. Nguyen   +17 more
doaj   +1 more source

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