Results 1 to 10 of about 100,615 (218)

Levosimendan in lung transplant recipients on VA‑ECMO

Вестник трансплантологии и искусственных органов, 2020
Chronic heart failure is one of the most dreadful complications in the early postoperative period following lung transplantation. At the same time, the effect of using levosimendan in the early post-lung transplant period is currently insignificant and ...
S. V. Zhuravel, V. E. Aleksandrova, I. I. Utkina, N. K. Kuznetsova, E. A. Tarabrin   +4 more
doaj   +1 more source

Biomimetic electromechanical stimulation to maintain adult myocardial slices in vitro

Nature Communications, 2019
Cultured adult cardiac tissue undergoes rapid dedifferentiation, which hinders chronic in vitro studies. Here the authors investigate biomimetic electromechanical stimulation of adult myocardial slices applying different preload conditions, identifying ...
Samuel A. Watson, James Duff, Ifigeneia Bardi, Magdalena Zabielska, Santosh S. Atanur, Richard J. Jabbour, André Simon, Alejandra Tomas, Ryszard T. Smolenski, Sian E. Harding, Filippo Perbellini, Cesare M. Terracciano   +11 more
doaj   +1 more source

Regression of renal cell carcinoma by T cell receptor-engineered T cells targeting a human endogenous retrovirus

Journal for ImmunoTherapy of Cancer
Background We discovered a novel human endogenous retrovirus (CT-RCC HERV-E) that was selectively expressed in most clear cell renal cell carcinomas (ccRCC) and served as a source of antigens for T cell-mediated killing. Here, we described the cloning of
Long Chen, David F Stroncek, Gang Zeng, Steven Highfill, Robert Reger, Stefan Barisic, Elena Cherkasova, Elizabeth M Brahmbhatt, Timothy T Spear, Ujjawal Savani, Stephanie Pierre, Gina M Scurti, Muna Igboko, Rosa Nadal, Gordon Parry, Annika V Dalheim, Michael I Nishimura, Richard W Childs   +17 more
doaj   +1 more source

An early nationwide analysis on the continuous distribution of lung-involved multiorgan transplantationCentral MessagePerspective

JTCVS Open
Background: The impact of continuous distribution on allocation of multiorgan transplantation (MOT) involving lungs remains unexplored. Here we characterize how continuous distribution has affected lung-involved MOT. Methods: We conducted a retrospective
Haoran Jiang, MS, Isaac S. Alderete, MD, MHS, Alexandria L. Soto, MA, Matthew Libre, BA, Samantha E. Halpern, MD, MHS, Oliver K. Jawitz, MD, MHS, Joshua A. Rushakoff, MD, MPP, Benjamin R. Helmold, BA, Kunal J. Patel, MD, PhD, Hiroshi Date, MD, PhD, Jacob Klapper, MD, MHS, Matthew G. Hartwig, MD, MHS   +11 more
doaj   +1 more source

2015 ESC/ERS GUIDELINES FOR THE DIAGNOSIS AND TREATMENT OF PULMONARY HYPERTENSION

Российский кардиологический журнал, 2016
The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS)Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC ...
Nazzareno Galiè, Marc Humbert, Jean-Luc Vachiery, Simon Gibbs, Irene Lang, Adam Torbicki, Gérald Simonneau, Andrew Peacock, Anton Vonk Noordegraaf, Maurice Beghetti, Ardeschir Ghofrani, Miguel Angel Gomez Sanchez, Georg Hansmann, Walter Klepetko, Patrizio Lancellotti, Marco Matucci, Theresa McDonagh, Luc A. Pierard, Pedro T. Trindade, Maurizio Zompatori, Marius Hoeper   +20 more
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Indications for Lung Transplantation and Patient Selection

Journal of Chest Surgery, 2022
Globally, thousands of patients undergo lung transplantation owing to end-stage lung disease each year. As lung transplantation evolves, recommendations and indications are constantly being updated. In 2021, the International Society for Heart and Lung
Joohyung Son, Changwon Shin
doaj   +1 more source

Suppressor of IKKɛ is an essential negative regulator of pathological cardiac hypertrophy

Nature Communications, 2016
Although pathological cardiac hypertrophy represents a leading cause of morbidity and mortality worldwide, our understanding of the molecular mechanisms underlying this disease is still poor.
Ke-Qiong Deng, Aibing Wang, Yan-Xiao Ji, Xiao-Jing Zhang, Jing Fang, Yan Zhang, Peng Zhang, Xi Jiang, Lu Gao, Xue-Yong Zhu, Yichao Zhao, Lingchen Gao, Qinglin Yang, Xue-Hai Zhu, Xiang Wei, Jun Pu, Hongliang Li   +16 more
doaj   +1 more source

Overexpression of hypoxia-inducible factor 1 alpha improves immunomodulation by dental mesenchymal stem cells

Stem Cell Research & Therapy, 2017
Background Human dental mesenchymal stem cells (MSCs) are considered as highly accessible and attractive MSCs for use in regenerative medicine, yet some of their features are not as well characterized as other MSCs.
Victor G. Martinez, Imelda Ontoria-Oviedo, Carolina P. Ricardo, Sian E. Harding, Rosa Sacedon, Alberto Varas, Agustin Zapata, Pilar Sepulveda, Angeles Vicente   +8 more
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Primary graft dysfunction prevention strategies in the perioperative period

JHLT Open
Background: Primary graft dysfunction (PGD) remains a leading cause of early morbidity and mortality after heart and lung transplantation. It results from a multifactorial process involving ischemia–reperfusion injury, inflammatory and immune responses ...
Jérémie Guillemin, MD, Michael Cutrone, DO, Suraj Yalamuri, MD, Monica Arndt, MD, Adrien Bouglé, MD, PhD, Sharon L. McCartney, MD, FASE   +5 more
doaj   +1 more source

Single-Kidney Transplant on VA-ECMO While Recovering from Post-Heart-Transplant Graft Failure

Case Reports in Critical Care, 2018
Although no consensus exists on whether extracorporeal membrane oxygenation (ECMO) support is an indication for solid-organ transplantation other than heart and lung, this practice continues to be limited.
Gabriel Prada, Anjali Agarwal, Jose L. Diaz-Gomez, Robert A. Ratzlaff   +3 more
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