Results 1 to 10 of about 93,728 (135)

Heart-lung transplantation for idiopathic pulmonary arterial hypertension and giant pulmonary artery aneurysm – case report [PDF]

open access: yesJournal of Cardiothoracic Surgery, 2020
Backgound Idiopathic pulmonary arterial hypertension (IPAH) is a rare condition that requires lung transplantation in patients’ refractory to medical therapy.
T. Eadington   +2 more
doaj   +2 more sources

Heart-lung transplantation. [PDF]

open access: yesJ Thorac Dis, 2014
Heart-lung transplantation itself is not a particularly difficult operation technically. It is the setting in which this procedure is performed which is difficult. The three issues of importance in a successful outcome are appropriate harvest of the heart-lung bloc from the donor, careful explant of the heart and lungs of the recipient, and finally the
Huddleston CB, Richey SR.
europepmc   +3 more sources

Heart-Lung Transplantation

open access: yesInvestigative Radiology, 1989
Since the successful clinical reintroduction of heart and lung transplantation in 1981, more than 350 of these procedures have been performed worldwide. Although survival following this operation is less than that reported for heart transplantation, the results are improving. It is clear that the increased technical difficulty of the procedure combined
R S, Bonser   +2 more
  +12 more sources

Evolution of the Surgical Management of Lung Cancer Invading the Spine: A Single Center Experience

open access: yesCurrent Oncology, 2022
For patients with locally advanced non-small cell lung cancer invading the spine, induction chemoradiotherapy combined with radical en bloc resection is the key to obtaining long-term survival.
Gabrielle Drevet   +8 more
doaj   +1 more source

Heart-Lung Transplantation

open access: yesClinics in Chest Medicine, 1990
The results of combined heart-lung transplantation have continued to improve following its reintroduction into clinical practice in 1981. En-bloc implantation has an apparent protective effect on subsequent tracheal anastomotic healing. Continuing developments in immunosuppression, rejection surveillance, and organ preservation will allow the procedure
R S, Bonser, S W, Jamieson
  +6 more sources

High-affinity CD16 integration into a CRISPR/Cas9-edited CD38 locus augments CD38-directed antitumor activity of primary human natural killer cells

open access: yesJournal for ImmunoTherapy of Cancer, 2022
Background Adoptive transfer of natural killer (NK) cells with augmented antibody-dependent cellular cytotoxicity (ADCC) capabilities and resistance to CD38 targeting has the potential to enhance the clinical anti-myeloma activity of daratumumab (DARA ...
Long Chen   +8 more
doaj   +1 more source

Lung Transplantation for Pulmonary Arterial Hypertension: Optimized Referral and Listing Based on an Evolving Disease Concept

open access: yesJournal of Cardiovascular Development and Disease, 2023
Pulmonary hypertension (PH) was once a devastating and fatal disease entity, the outlook of which has been significantly improved by the continued progress of medical treatment algorithms.
Xiaokun Hu   +9 more
doaj   +1 more source

Cardiac Imaging in Patients After Fontan Palliation: Which Test and When?

open access: yesFrontiers in Pediatrics, 2022
The Fontan operation represents the final stage of a series of palliative surgical procedures for children born with complex congenital heart disease, where a “usual” biventricular physiology cannot be restored.
Paolo Ciliberti   +10 more
doaj   +1 more source

Systematic improvements in lentiviral transduction of primary human natural killer cells undergoing ex vivo expansion

open access: yesMolecular Therapy: Methods & Clinical Development, 2021
Transduction of primary human natural killer (NK) cells with lentiviral vectors has historically been challenging. We sought to evaluate multiple parameters to optimize lentiviral transduction of human peripheral blood NK cells being expanded to large ...
David S.J. Allan   +6 more
doaj   +1 more source

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