Results 231 to 240 of about 184,554 (278)

Lithospermic Acid Improves Doxorubicin‐Induced Cardiomyopathy Through Sirtuin‐3‐Mediated Deacetylation of p53

Phytotherapy Research, EarlyView.
Lithospermic acid (LA) inactivates the p53 signaling pathway via directly targeting SIRT3, thereby alleviating oxidative stress and abnormal apoptosis in the progression of doxorubicin (Dox)‐induced cardiomyocytes. ABSTRACT Doxorubicin (Dox)‐induced cardiomyopathy (DIC) is characterized by significant myocardial damage that can progress to dilated ...
Yining Zhao, Tao Xu, Chao Ye, Ke Zhang, Xinyu Heng, Shaohong Huang, Yan Chen, Yitong Guo, Shengyi Shao, Zhi Wen, Chenwen Shao, Xiang Lu, Ning Sun, Hai Yang   +13 more
wiley   +1 more source

PHENOTYPIC T-CELL CHANGES IN THORACIC TRANSPLANT RECIPIENTS IMMUNOSUPPRESSED WITH FK506 [PDF]

, 1991
ARMITAGE, J, DUQUESNOY, R, GRIFFITH, B, KAUFMAN, C, KEENAN, R, KORMOS, R, STARZL, T, YOUSEM, S, ZEEVI, A, ZERBE, T   +9 more
core  

Pharmacological Inhibition of APT2 by Solasonine Promotes Ferroptosis Through Palmitoylation Modulation in Gallbladder Cancer

Phytotherapy Research, EarlyView.
Schematic illustration of SS‐induced ferroptosis through targeting APT2‐mediated STAT3 palmitoylation in GBC cells. ABSTRACT Gallbladder cancer (GBC), the most prevalent and lethal biliary tract malignancy, lacks effective therapeutic strategies. Solasonine (SS), a bioactive steroidal alkaloid derived from Solanum nigrum L, exhibits antitumor activity ...
Liu‐qing Shi, Jing‐wei Zhao, Jia‐yun Zhu, Cheng Zhao, Zi‐yi Yang, Li‐jia Pan, Ben Ma, Zheng‐yu Chen, Zi‐ying Wang, Chun‐jie Li, Shi‐lei Liu, Jia‐wei Mei, Ping Dong   +12 more
wiley   +1 more source

Control of post-transplant lymphoproliferative disorders and Kaposi's sarcoma by modulation of immunosuppression [PDF]

, 1987
Breinig, MK, Demetris, AJ, Griffith, BP, Ho, M, Iwatsuki, S, Jaffe, R, Makowka, L, Nalesnik, M, Starzl, TE, Steiber, A, Tzakis, A   +10 more
core  

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

Bilateral lung transplantation with simultaneous aortic replacement using donor aorta in a patient with pulmonary arterial hypertension and patent ductus arteriosus. [PDF]

J Cardiothorac Surg
Ishida N, Oishi H, Niikawa H, Suzuki T, Notsuda H, Hirama T, Watanabe T, Watanabe Y, Togo T, Onodera K, Kumata S, Suzuki Y, Ito T, Taketomi R, Katahira S, Kumagai K, Saiki Y, Okada Y.   +17 more
europepmc   +1 more source

A fully magnetically levitated left ventricular assist device — final report [PDF]

, 2019
Ewald, G.A., Itoh, A.
core   +1 more source

Cardiac disease in systemic sclerosis: Integrating pathobiology with clinical management

Rheumatology &Autoimmunity, EarlyView.
Abstract Systemic sclerosis (SSc) is a complex autoimmune disorder in which cardiovascular involvement remains a major determinant of morbidity and mortality. Cardiac injury in SSc results from the interplay of microvascular dysfunction, immune‐mediated inflammation, and progressive interstitial and replacement fibrosis, leading to myocardial disease ...
Henry Sutanto, Betty Rachma, Yuliasih
wiley   +1 more source

Non-Melanoma Skin Cancer in Transplant Recipients: A Single-Centre Retrospective Cohort Study on the Role of Transplant Type, Immunosuppressive Exposure, and Tumor Subtypes. [PDF]

Clin Transplant
Zengarini C, Tagnin V, Sorbi G, Guglielmo A, La Placa M, Piraccini BM, Pileri A, Pignatti M.   +7 more
europepmc   +1 more source

Orthotopic heart transplantation for Fontan failure: experience and treatment strategy-a case report. [PDF]

Gen Thorac Cardiovasc Surg Cases
Horie S, Shikata F, Hirata Y, Tsuji S, Moriyama S, Ando M, Inuzuka R, Kato H, Ono M.   +8 more
europepmc   +1 more source