Results 21 to 30 of about 185,979 (321)

Expanded NK cells used for adoptive cell therapy maintain diverse clonality and contain long-lived memory-like NK cell populations

open access: yesMolecular Therapy: Oncolytics, 2023
Multiple clinical trials exploring the potential of adoptive natural killer (NK) cell therapy for cancer have employed ex vivo expansion using feeder cells to obtain large numbers of NK cells.
David S.J. Allan   +7 more
doaj   +1 more source

Heart transplantation in a patient with complex heart lung disease: a case report

open access: yesKorean Journal of Transplantation, 2021
Heart disease is often accompanied by lung disease as they share the same risk factors. Heart or lung transplantation is regarded as a definitive treatment for the end-stage disease of each, while the expected median survival for lung transplantation is ...
Seok Hyun Kim   +3 more
doaj   +1 more source

Totally endoscopic non-robotic excision of aortic valve fibroelastoma: a case report

open access: yesJournal of Cardiothoracic Surgery, 2022
Background Papillary fibroelastomas (PFEs) are a rare subtype of benign primary cardiac tumours, which are most commonly found on the aortic valve. Although median sternotomy is still used frequently there has been different attempts to remove the aortic
Sadia Batool   +3 more
doaj   +1 more source

Integrating Bulk Transcriptome and Single-Cell RNA Sequencing Data Reveals the Landscape of the Immune Microenvironment in Thoracic Aortic Aneurysms

open access: yesFrontiers in Cardiovascular Medicine, 2022
Thoracic aortic aneurysm (TAA) is a life-threatening cardiovascular disease whose formation is reported to be associated with massive vascular inflammatory responses.
Qunhui Wang   +12 more
doaj   +1 more source

Factors influencing transfusion-associated HLA sensitization in patients bridged to heart transplantation using ventricular assist device. [PDF]

open access: yes, 2020
BackgroundBridging heart failure patients with mechanical ventricular assist devices (VAD) enables access to transplantation. However, VAD is associated with increased risk for anti-HLA antibodies associated with rejection of subsequent allografts ...
Adler, Eric   +5 more
core   +1 more source

BRD4770 functions as a novel ferroptosis inhibitor to protect against aortic dissection

open access: yesPharmacological Research, 2022
Smooth muscle cell (SMC) loss is the characteristic feature in the pathogenesis of aortic dissection (AD), and ferroptosis is a novel iron-dependent regulated cell death driven by the excessive lipid peroxidation accumulation.
Yue Chen   +11 more
doaj   +1 more source

Perioperative donor bone marrow infusion augments chimerism in heart and lung transplant recipients [PDF]

open access: yes, 1995
Background.: We and others have demonstrated that a low level of donor cell chimerism was present for years after transplantation in tissues and peripheral blood of heart and lung recipients; it was associated, in the latter, with a lower incidence of ...
Abdul S. Rao   +34 more
core   +1 more source

Upregulation of IRF9 Contributes to Pulmonary Artery Smooth Muscle Cell Proliferation During Pulmonary Arterial Hypertension

open access: yesFrontiers in Pharmacology, 2021
Abnormal proliferation of pulmonary artery smooth muscle cells (PASMCs) is a critical pathological feature in the pathogenesis of pulmonary arterial hypertension (PAH), but the regulatory mechanisms remain largely unknown.
Yong-Jie Chen   +14 more
doaj   +1 more source

Reversibility of lymphomas and lymphoproliferative lesions developing under cyclosporin-steroid therapy [PDF]

open access: yes, 1984
Post-transplant lymphomas or other lymphoproliferative lesions, which were usually associated with Epstein-Barr virus infections, developed in 8, 4, 3, and 2 recipients, respectively, of cadaveric kidney, liver, heart, and heart-lung homografts ...
Atchison, RW   +12 more
core   +1 more source

The Modern Surgical Approach to Pulmonary Atresia with Ventricular Septal Defect and Major Aortopulmonary Collateral Arteries

open access: yesChildren, 2022
Pulmonary atresia with ventricular septal defect and major aortopulmonary collaterals is a complex congenital heart defect that includes a heterogeneous subgroup of patients.
Matteo Trezzi   +5 more
doaj   +1 more source

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