Results 1 to 10 of about 16,119 (209)

Imaging cardiac sympathetic innervation with MIBG: linear conversion of the heart-to-mediastinum ratio between different collimators [PDF]

EJNMMI Physics, 2019
Background The heart-to-mediastinum (H/M) ratio is a commonly used parameter to measure cardiac I-123 metaiodobenzylguanidine (MIBG) uptake. Since the H/M ratio is substantially influenced by the collimator type, we investigated whether an empirical ...
Joachim Brumberg, Ganna Blazhenets, Nils Schröter, Lars Frings, Wolfgang H. Jost, Constantin Lapa, Philipp T. Meyer   +6 more
doaj   +10 more sources

Cardiac sympathetic dysfunction in pulmonary arterial hypertension: lesson from left-sided heart failure [PDF]

Pulmonary Circulation, 2019
Sympathetic nervous system hyperactivity has a well-recognized role in the pathophysiology of heart failure with reduced left ventricular ejection fraction.
Valentina Mercurio, Teresa Pellegrino, Giorgio Bosso, Giacomo Campi, Paolo Parrella, Valentina Piscopo, Carlo G. Tocchetti, Paul M. Hassoun, Mario Petretta, Alberto Cuocolo, Domenico Bonaduce   +10 more
doaj   +2 more sources

Effect of tofogliflozin on cardiac sympathetic nerve activity in type 2 diabetes mellitus patients with heart failure (TARGET-HF): rationale and design of the single-arm intervention trial [PDF]

Cardiovascular Diabetology. Endocrinology Reports
Background Cardiac sympathetic nervous dysfunction is linked to poor prognosis in heart failure with reduced ejection fraction (HFrEF), and patients with HFrEF complicated by type 2 diabetes mellitus (T2DM) represent a particularly high risk.
Takahiro Okumura, Yasuko K Bando, Satoshi Isobe, Naotoshi Fujita, Fusako Sera, Yuki Ikeda, Ayumu Yajima, Toshiyuki Nagai, Hiroaki Hiraiwa, Ryota Morimoto, Toshihisa Anzai, Koichi Node, Junya Ako, Yasushi Sakata, Toyoaki Murohara   +14 more
doaj   +2 more sources

Vascular time-activity variation in patients undergoing I-MIBG myocardial scintigraphy: implications for quantification of cardiac and mediastinal uptake [PDF]

, 2011
For the quantification of cardiac (123)I-metaiodobenzylguanidine (MIBG) uptake, the mediastinum is commonly used as a reference region reflecting nonspecific background activity.
Verberne, Hein J., Verschure, Derk O., Somsen, G. Aernout, van Eck-Smit, Berthe L. F., Jacobson, Arnold F.   +4 more
core   +14 more sources

Cardiac ¹²³I-mIBG Imaging in Heart Failure

Pharmaceuticals, 2022
Cardiac sympathetic upregulation is one of the neurohormonal compensation mechanisms that play an important role in the pathogenesis of chronic heart failure (CHF).
Derk O. Verschure, Kenichi Nakajima, Hein J. Verberne   +2 more
doaj   +1 more source

Changes in cardiac sympathetic nerve activity on 123I‐metaiodobenzylguanidine scintigraphy after MitraClip therapy

ESC Heart Failure, 2021
Aims In patients with heart failure, over‐activation of the cardiac sympathetic nerve (CSN) function is associated with severity of heart failure and worse outcome.
Keisuke Fukuda, Seiji Hasegawa, Tomonori Kawamura, Naoto Waratani, Kumiko Hirata, Akihiro Higashimori, Yoshiaki Yokoi   +6 more
doaj   +1 more source

Convolutional neural network-based automatic heart segmentation and quantitation in 123I-metaiodobenzylguanidine SPECT imaging

EJNMMI Research, 2021
Background Since three-dimensional segmentation of cardiac region in 123I-metaiodobenzylguanidine (MIBG) study has not been established, this study aimed to achieve organ segmentation using a convolutional neural network (CNN) with 123I-MIBG single ...
Shintaro Saito, Kenichi Nakajima, Lars Edenbrandt, Olof Enqvist, Johannes Ulén, Seigo Kinuya   +5 more
doaj   +1 more source

The relation between cardiac 123I-mIBG scintigraphy and functional response 1 year after CRT implantation [PDF]

, 2020
Cardiac resynchronization therapy (CRT) is a disease-modifying therapy in patients with chronic heart failure (CHF). Current guidelines ascribe CRT eligibility on three parameters only: left ventricular ejection fraction (LVEF), QRS duration, and New ...
de Groot, J R, De Vincentis, G, Frantellizzi, V, Gheysens, O, Nakajima, K, Poel, E, Verberne, H J, Verschure, D O   +7 more
core   +1 more source

Proning: Its anatomical basis and effect on oxygen saturation in COVID patients

National Journal of Clinical Anatomy, 2021
Proning is the process of turning the patient from their supine (lying on their back) position to lying on their abdomen. It is a medically accepted position for improving oxygenation while breathing.
N B Pushpa, S Viveka, K S Ravi, Vishwambar Vallabhaneni   +3 more
doaj   +1 more source

Prediction of long-term cardiac events by 123I-MIBG imaging after acute myocardial infarction and reperfusion therapy [PDF]

Asia Oceania Journal of Nuclear Medicine and Biology, 2019
Objective(s): In heart failure, the heart-to-mediastinum (H/M) ratio of the delayed image and washout rate (WR) are well-known as a powerful cardiac event predictors.
Manabu Nakamura, Masahisa Onoguchi, Takayuki Shibutani   +2 more
doaj   +1 more source