Results 31 to 40 of about 389,551 (274)

Senescence mechanisms and targets in the heart.

Cardiovascular Research, 2021
Cellular senescence is a state of irreversible cell cycle arrest associated with ageing. Senescence of different cardiac cell types can direct the pathophysiology of cardiovascular diseases such as atherosclerosis, myocardial infarction, and cardiac ...
Maggie Chen, Richard T. Lee, J. Garbern
semanticscholar   +1 more source

Non-Invasive Monitoring of Core Body Temperature for Targeted Temperature Management in Post-Cardiac Arrest Care

Frontiers in Medicine, 2022
ImportanceAccurate monitoring of core body temperature is integral to targeted temperature management (TTM) following cardiac arrest. However, there are no reliable non-invasive methods for monitoring temperature during TTM.ObjectivesWe compared the ...
Kyle Fiorini, Kyle Fiorini, Tanya Tamasi, Justin Dorie, Ahmed F. Hegazy, Ahmed F. Hegazy, Ting-Yim Lee, Ting-Yim Lee, Marat Slessarev, Marat Slessarev, Marat Slessarev   +10 more
doaj   +1 more source

Brain Death and Its Prediction in Out-of-Hospital Cardiac Arrest Patients Treated with Targeted Temperature Management

Diagnostics, 2022
Evolution toward brain death (BD) in out-of-hospital cardiac arrest patients with targeted temperature management (TTM) provides opportunities for organ donation. However, knowledge regarding BD in these patients is limited.
Hwan Song, Sang Hoon Oh, Hye Rim Woo, on behalf of CROWN Investigators   +3 more
doaj   +1 more source

Beyond dichotomy: patterns and amplitudes of SSEPs and neurological outcomes after cardiac arrest

Critical Care, 2019
Background We hypothesized that the absence of P25 and the N20–P25 amplitude in somatosensory evoked potentials (SSEPs) have higher sensitivity than the absence of N20 for poor neurological outcomes, and we evaluated the ability of SSEPs to predict long ...
Sang Hoon Oh, Kyu Nam Park, Seung Pill Choi, Joo Suk Oh, Han Joon Kim, Chun Song Youn, Soo Hyun Kim, Kiyuk Chang, Seong Hoon Kim   +8 more
doaj   +1 more source

Targeted Temperature Management at 36°C after In-Hospital Cardiac Arrest Trial (TTM-36 IHCA Trial): Study Protocol for an Investigator-Initiated, Single-Center, Randomized, Controlled, Assessor-Blinded, Pilot Clinical Trial [PDF]

Journal of Neurocritical Care, 2016
Background: Targeted temperature management (TTM) has neuroprotective effects in comatose patients despite restoration of spontaneous circulation (ROSC) after out-of-hospital cardiac arrest.

doaj   +1 more source

Therapeutic hypothermia and neurological outcome after cardiac arrest [PDF]

Vojnosanitetski Pregled, 2011
Introduction/Aim. The most important clinically relevant cause of global cerebral ischemia is cardiac arrest. Clinical studies showed a marked neuroprotective effect of mild hypothermia in resuscitation.
Petrović Milovan, Panić Gordana, Jovelić Aleksandra, Čanji Tibor, Srdanović Ilija, Popov Tanja, Golubović Miodrag   +6 more
doaj   +1 more source

Optogenetic manipulation of neuronal and cardiomyocyte functions in zebrafish using microbial rhodopsins and adenylyl cyclases

eLife, 2023
Even though microbial photosensitive proteins have been used for optogenetics, their use should be optimized to precisely control cell and tissue functions in vivo.
Hanako Hagio, Wataru Koyama, Shiori Hosaka, Aysenur Deniz Song, Janchiv Narantsatsral, Koji Matsuda, Takashi Shimizu, Shoko Hososhima, Satoshi P Tsunoda, Hideki Kandori, Masahiko Hibi   +10 more
doaj   +1 more source

Correlation between end-tidal carbon dioxide and the degree of compression of heart cavities measured by transthoracic echocardiography during cardiopulmonary resuscitation for out-of-hospital cardiac arrest

Critical Care, 2019
BackgroundThe concept of personalized cardiopulmonary resuscitation (CPR) requires a parameter that reflects its hemodynamic efficiency. While intra-arrest ultrasound is increasingly implemented into the advanced life support, we realized a pre-hospital ...
R. Skulec, P. Vojtíšek, V. Černý
semanticscholar   +1 more source

Post-operative cardiac arrest induced by co-administration of amiodarone and dexmedetomidine: a case report

Journal of Intensive Care, 2015
We firstly report a postoperative hemodialysis patient who was co-administered with amiodarone and dexmedetomidine and developed severe bradycardia followed by cardiac arrest.
Takafumi Ohmori, Nobuhiro Shiota, Akihiro Haramo, T. Masuda, Fumi Maruyama, K. Wakabayashi, Y. Adachi, K. Nakazawa   +7 more
semanticscholar   +1 more source

Omecamtiv mecarbil treatment improves post-resuscitation cardiac function and neurological outcome in a rat model.

PLoS ONE, 2022
BackgroundMyocardial dysfunction is a major cause of poor outcomes in the post-cardiac arrest period. Omecamtiv mecarbil (OM) is a selective small molecule activator of cardiac myosin that prolongs myocardial systole and increases stroke volume without ...
Shih-Ni Wu, Min-Shan Tsai, Chien-Hua Huang, Wen-Jone Chen   +3 more
doaj   +2 more sources