Results 41 to 50 of about 234,954 (310)

Atherosusceptible Shear Stress Activates Endoplasmic Reticulum Stress to Promote Endothelial Inflammation. [PDF]

open access: yes, 2017
Atherosclerosis impacts arteries where disturbed blood flow renders the endothelium susceptible to inflammation. Cytokine activation of endothelial cells (EC) upregulates VCAM-1 receptors that target monocyte recruitment to atherosusceptible regions ...
Bailey, Keith A   +3 more
core   +1 more source

Galectin-12 in Cellular Differentiation, Apoptosis and Polarization. [PDF]

open access: yes, 2018
Galectin-12 is a member of a family of mammalian lectins characterized by their affinity for β-galactosides and consensus amino acid sequences. The protein structure consists of a single polypeptide chain containing two carbohydrate-recognition domains ...
Liu, Fu-Tong, Wan, Lei, Yang, Ri-Yao
core   +2 more sources

Evaluation of the Appropriate Root Pressure for Maintaining Heartbeat during an Aortic Cross-clamp for Primary Repair of the Aortic Arch in Premature Infants with Associated Cardiac Anomalies [PDF]

open access: yes, 2010
We developed a new cardiopulmonary bypass (CPB) method to minimize myocardial damage during aortic arch reconstruction. In this method, coronary flow and heartbeat were stabilized by maintaining the aortic root pressure with an adjusted preload of the ...
Honjo, Osami   +5 more
core   +1 more source

The Use of Adenosine to Enable Safe Implantation of Transcatheter Tricuspid Valve

open access: yesCase Reports in Cardiology, 2017
High precision is necessary during percutaneous transcatheter heart valve implantation. The precision of the implantation has been established by increasing the heart rate (usually to 200 beats per minute) to the point of significantly reduced cardiac ...
Vicki Zeniou   +5 more
doaj   +1 more source

Intralipid fails to rescue bupivacaine-induced cardiotoxicity in late-pregnant rats

open access: yesFrontiers in Medicine, 2022
BackgroundFemales routinely receive bupivacaine for obstetric and regional anesthesia. An accidental overdose of bupivacaine can result in cardiotoxicity and cardiac arrest.
Caitlin Sherman   +7 more
doaj   +1 more source

Oklahoma Heart Hospital: Clinician Leaders Establish Culture of Quality [PDF]

open access: yes, 2009
Describes strategies for a culture of quality, including a flat organizational structure, optimal nurse experience and ratios, standardization through care sets, technology-enabled feedback and assessment, and continuous improvement through new ...
Sharon Silow-Carroll
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Cardiorespiratory depression from brainstem seizure activity in freely moving rats

open access: yesNeurobiology of Disease, 2020
Cardiorespiratory dysfunction during or after seizures may contribute to sudden unexpected death in epilepsy. Disruption of lower brainstem cardiorespiratory systems by seizures is postulated to impair respiratory and cardiac function.
Wanida Lertwittayanon   +2 more
doaj   +1 more source

Histopathological analysis and in situ localisation of Australian tiger snake venom in two clinically envenomed domestic animals [PDF]

open access: yes, 2011
Objective: To assess histopathological changes in clinically envenomed tiger snake patients and identify tissue specific localisation of venom toxins using immunohistochemistry.
Balmer, L.   +5 more
core   +2 more sources

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