Targeted Temperature Management at 36°C after In-Hospital Cardiac Arrest Trial (TTM-36 IHCA Trial): Study Protocol for an Investigator-Initiated, Single-Center, Randomized, Controlled, Assessor-Blinded, Pilot Clinical Trial [PDF]
Background: Targeted temperature management (TTM) has neuroprotective effects in comatose patients despite restoration of spontaneous circulation (ROSC) after out-of-hospital cardiac arrest.
doaj +1 more source
Effect of Trans-Nasal Evaporative Intra-arrest Cooling on Functional Neurologic Outcome in Out-of-Hospital Cardiac Arrest : The PRINCESS Randomized Clinical Trial [PDF]
© 2019 American Medical Association. All rights reserved.Importance: Therapeutic hypothermia may increase survival with good neurologic outcome after cardiac arrest.
Abella +43 more
core +3 more sources
Sudden cardiac arrest is a leading cause of death in the United States. The neurophysiological mechanism underlying sudden death is not well understood.
Fangyun Tian +18 more
doaj +1 more source
Alternative Splicing of Pericentrin Contributes to Cell Cycle Control in Cardiomyocytes
Induction of cardiomyocyte proliferation is a promising option to regenerate the heart. Thus, it is important to elucidate mechanisms that contribute to the cell cycle arrest of mammalian cardiomyocytes.
Jakob Steinfeldt +3 more
doaj +1 more source
Cardiovascular Remodeling Experienced by Real-World, Unsupervised, Young Novice Marathon Runners. [PDF]
Aims: Marathon running is a popular ambition in modern societies inclusive of non-athletes. Previous studies have highlighted concerning transient myocardial dysfunction and biomarker release immediately after the race.
Aengevaeren +92 more
core +2 more sources
To investigate Stone Heart Syndrome (SHS) as consequence of prolonged ischemic arrest in an experimental study on pigs in regards to onset of SHS and pathological changes. Outcomes defined as aortic cross clamp (ACC) time until onset of SHS and cellular changes characterized by SHS.Eight pigs were included to undergo normothermic cardioplegia induced ...
Lytfi Krasniqi +6 more
openaire +2 more sources
Long-term deficits in cortical circuit function after asphyxial cardiac arrest and resuscitation in developing rats [PDF]
Cardiac arrest is a common cause of global hypoxic-ischemic brain injury. Poor neurologic outcome among cardiac arrest survivors results not only from direct cellular injury but also from subsequent long-term dysfunction of neuronal circuits.
Clark, Robert S.B. +5 more
core +2 more sources
Introduction: Few data can be found about cardiac arrest in the intensive care unit outside reference centers in third world countries. Objective: To study epidemiology and prognostic factors associated with cardiac arrest in the intensive care unit ...
Leonardo Augusto Miana +6 more
doaj +1 more source
Dissociation of Cerebral Blood Flow and Femoral Artery Blood Pressure Pulsatility After Cardiac Arrest and Resuscitation in a Rodent Model: Implications for Neurological Recovery. [PDF]
Background Impaired neurological function affects 85% to 90% of cardiac arrest (CA) survivors. Pulsatile blood flow may play an important role in neurological recovery after CA.
Akbari, Yama +6 more
core +1 more source
Rat model of asphyxia-induced cardiac arrest and resuscitation
Neurologic injury after cardiopulmonary resuscitation is the main cause of the low survival rate and poor quality of life among patients who have experienced cardiac arrest.
Shuhang Yu +4 more
doaj +1 more source

