Results 51 to 60 of about 46,815 (263)

Structural and functional characteristics of myocard in patients with different forms of atrial fibrillation

open access: yesZaporožskij Medicinskij Žurnal, 2015
Aim. To study structural and functional characteristics of myocard in patients with different forms of atrial fibrillation. Atrial fibrillation is the most prevalent arrhythmia in clinical practice.
L. I. Vasilyeva   +4 more
doaj   +1 more source

Cardiac specific expression of threonine 5 to alanine mutant sarcolipin results in structural remodeling and diastolic dysfunction. [PDF]

open access: yesPLoS ONE, 2015
The functional importance of threonine 5 (T5) in modulating the activity of sarcolipin (SLN), a key regulator of sarco/endoplasmic reticulum (SR) Ca2+ ATPase (SERCA) pump was studied using a transgenic mouse model with cardiac specific expression of ...
Mayilvahanan Shanmugam   +9 more
doaj   +1 more source

Bioinspired Passive Flow Routing to Mitigate Thrombosis in Prosthetic Heart Valves and Cardiovascular Devices

open access: yesAdvanced Science, EarlyView.
Bioinspired passive flow routing mitigates thrombosis in cardiovascular devices by redirecting a small fraction of forward flow into stagnation‐prone regions. Inspired by avian alula and aircraft slat mechanisms, strategically placed routing channels restore washout around mechanical heart valves, reducing low‐shear exposure by four orders of magnitude
Yevgeniy Kreinin   +8 more
wiley   +1 more source

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

open access: yesAdvanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai   +9 more
wiley   +1 more source

Unusual Giant Right Atrium in Rheumatic Mitral Stenosis and Tricuspid Insufficiency

open access: yesCase Reports in Cardiology, 2011
Dilation and hypertrophy of the atria occur in patients with valvular heart disease especially in mitral regurgitation, mitral stenosis or tricuspid abnormalities.
Jean Baptiste Anzouan-Kacou   +6 more
doaj   +1 more source

The absence of dystrophin brain isoform expression in healthy human heart ventricles explains the pathogenesis of 5' X-linked dilated cardiomyopathy

open access: yesBMC Medical Genetics, 2012
Background In X-linked dilated cardiomyopathy due to dystrophin mutations which abolish the expression of the M isoform (5'-XLDC), the skeletal muscle is spared through the up-regulation of the Brain (B) isoform, a compensatory mechanism that does not ...
Neri Marcella   +10 more
doaj   +1 more source

Vasoactive Intestinal Polypeptide in Rat Heart Atria: the Effect of Hyperthyroidism

open access: yesPhysiological Research, 2000
The effects of transient and sustained hyperthyroidism on vasoactive intestinal polypeptide-like immunoreactivity (VIP-LI) levels were studied in the heart atria of developing and adult rats. Newborn rats were divided into 5 groups. Neo-T animals were treated with thyroxine (T4) during postnatal days 1-8 and sacrificed at the age of 60 days. Neo-S rats
J, Kuncová, J, Slavíková
openaire   +2 more sources

Label‐Free Myelin Fingerprinting: An Adult Human Post‐Mortem Brain Slice Platform via Coherent Anti‐Stokes Raman Spectroscopy

open access: yesAdvanced Science, EarlyView.
A serum‐free, air–liquid interface organotypic slice culture model preserves human post‐mortem corpus callosum tissue, successfully recovering from slicing trauma to reflect the donor's underlying disease state. Pairing label‐free Coherent anti‐Stokes Raman scattering (CARS) microscopy with k‐means clustering enables objective, high‐resolution ...
Kasra Roya‐Kouchaki   +5 more
wiley   +1 more source

Intermittent Fasting Restores Cardiac Lipid Homeostasis in Diabetic Cardiomyopathy in Association With Akkermansia Muciniphila and 1‐methyl‐L‐histidine

open access: yesAdvanced Science, EarlyView.
Intermittent fasting reshapes the gut microbiota in diabetic cardiomyopathy, restoring Akkermansia muciniphila and the microbiota‐associated metabolite 1‐methyl‐L‐histidine. This shift is linked to improved cardiac lipid homeostasis, reduced lipid peroxidation, and attenuated myocardial injury, highlighting a gut microbiota–metabolite–lipid axis in ...
Kaiyuan Jiang   +7 more
wiley   +1 more source

CLINICAL CASE OF MULTIPLE HEART TUMORS IN NEWBORN

open access: yesМать и дитя в Кузбассе, 2019
Heart tumors are a rare pathology, especially in children. They have a varied characteristic. This disease can affect any part of the organ, the pericardium, the myocardium, the valves, the internal tissue of the heart, as well as the septum between the ...
Елена Викторовна Гольцман   +4 more
doaj  

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