Results 91 to 100 of about 5,481,660 (373)

Temporal Trends in the Incidence and Outcomes of Pacemaker Implantation After Transcatheter Aortic Valve Replacement in the United States (2012–2017)

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Nationwide studies documenting temporal trends in permanent pacemaker implantation (PPMI) following transcatheter aortic valve replacement (TAVR) are limited. Methods and Results We selected patients who underwent TAVR between 2012 and 2017 in
Akram Kawsara, Samian Sulaiman, Fahad Alqahtani, Mackram F. Eleid, Abhishek J. Deshmukh, Yong‐Mei Cha, Charanjit S. Rihal, Mohamad Alkhouli   +7 more
doaj   +1 more source

Sinus of Valsalva Aneurysm Dissecting into Interventricular Septum Compressing RVOT [PDF]

Journal of Clinical and Diagnostic Research, 2018
Aneurysm of sinus of valsalva is a rare disorder. Rupture of sinus of valsalva into the right atria, right ventricle and the left ventricle is more commonly seen.
Nishu Raj, Pallavi Sinha, Neeraj Wadhwa, Sunil Kumar Puri   +3 more
doaj   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

Real-time optical manipulation of cardiac conduction in intact hearts [PDF]

, 2018
Optogenetics has provided new insights in cardiovascular research, leading to new methods for cardiac pacing, resynchronization therapy and cardioversion.
Bocchi, L., Bub, G., Campione, M., Cannazzaro, S., Cerbai, E., Coppini, R., Crocini, C., Ferrantini, C., Giulietti, D., Loew, L.M., Margoni, E., Muellenbroich, C., Pavone, F.S., Poggesi, C., Sacconi, L., Scardigli, M., Yan, P.   +16 more
core   +2 more sources

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

An infrequent cause of apical ventricular aneurysm in the United States

Heart Views, 2017
Chronic Chagas cardiomyopathy (CCC) is a late complication of Chagas disease with various manifestations including arrhythmia, heart failure, thromboembolism, and stroke.
Mohammed M Taleb
doaj   +1 more source

Brain and heart‐specific death in cancer patients: Population‐based study

Cancer Medicine, 2021
Background The occurrence of cardiovascular events is a major cause of death in patients with cancer. Small studies have documented a connection between specific brain alterations and autonomic cardiac dysfunctions, possibly resulting in a worse ...
Mohammed Safi, Murad Al‐Nusaif, Dario Trapani, Mubarak A Mashrah, Ravindran Kanesvaran, Aziz Alzandani, Mahmoud Al‐Azab, Syed A Mazher, Abdullah Al‐Danakh, Jiwei Liu   +9 more
doaj   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Sex based disparities in hospitalization and readmission outcomes for complete atrioventricular block: Insights from United States readmission data

Journal of Arrhythmia
Background Sex disparities in cardiovascular disorders are well‐documented, but data on hospitalization and readmission outcomes in the context of sex for Complete Heart Block (CHB) remains limited.
Nadhem Abdallah, Mohammed Samra, Momen Alsayed   +2 more
doaj   +1 more source

Glimepiride, a novel sulfonylurea, does not abolish myocardial protection afforded by either ischemic preconditioning or diazoxide [PDF]

, 2001
Background: The sulfonylurea glibenclamide (Glib) abolishes the cardioprotective effect of ischemic preconditioning (IP), presumably by inhibiting mitochondrial KATP channel opening in myocytes. Glimepiride (Glim) is a new sulfonylurea reported to affect
Baxter, G.F., Lawrence, C.L., Maddock, H.L., Mocanu, M.M., Standen, N.B., Yellon, D.M.   +5 more
core