Results 91 to 100 of about 376,276 (314)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Minutes from the Heart Mountain Block Chairmen meeting, April 10, 1944 [PDF]

open access: yes, 1944
Minutes from the Heart Mountain Block Managers meeting.The Japanese American Archival Collection documents the people, places, and daily life of Japanese Americans, primarily those who lived in the once thriving community of pre-war Florin in the ...
Heart Mountain Block Chairmen
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Minutes from the Heart Mountain Block Chairmen meeting, special session, February 17, 1943 [PDF]

open access: yes, 1943
Minutes from the Heart Mountain Block Chairmen meeting. Includes discussion on "loyalty questionnaire" and Nisei.The Japanese American Archival Collection documents the people, places, and daily life of Japanese Americans, primarily those who lived in ...
Heart Mountain Block Chairmen
core  

Cardiac Arrhythmias and Conduction Disorders as the Main Manifestation of Chagas Myocarditis

open access: yesJuvenis Scientia
Introduction. Chagas disease is an infectious vector — borne disease caused by the protozoa Trypanosoma cruzi. The main manifestation of the chronic course of Chagas disease is myocarditis, which leads to chamber dilation, congestive heart failure, and ...
Timofeev, E.V.   +2 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Minutes from the Heart Mountain Block Chairmen meeting, January 23, 1943 [PDF]

open access: yes, 1943
Minutes from the Heart Mountain Block Chairmen meeting.The Japanese American Archival Collection documents the people, places, and daily life of Japanese Americans, primarily those who lived in the once thriving community of pre-war Florin in the ...
Heart Mountain Block Chairmen
core  

Bloqueio cardíaco completo em espondilite anquilosante Complete heart block in ankylosing spondylitis

open access: yesRevista Brasileira de Reumatologia, 2012
A espondilite anquilosante é uma doença reumática crônica de homens jovens que afeta principalmente o esqueleto axial e está associada ao HLA-B27 em 90% dos casos.
Juan Pablo Restrepo   +1 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Minutes from the Heart Mountain Block Chairmen meeting, January 7, 1943 [PDF]

open access: yes, 1943
Minutes from the Heart Mountain Block Chairmen meeting.The Japanese American Archival Collection documents the people, places, and daily life of Japanese Americans, primarily those who lived in the once thriving community of pre-war Florin in the ...
Heart Mountain Block Chairmen
core  

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