Results 301 to 310 of about 133,701 (359)

Angiocardiography [Abridged] [PDF]

Proceedings of the Royal Society of Medicine, 1963
openaire   +3 more sources

Quinoline ATP Synthase Inhibitors with Activity Against Multidrug Resistant Acinetobacter baumannii and Pseudomonas aeruginosa

ChemMedChem, EarlyView.
Targeting ATP synthase in Gram‐negative pathogens. Presented is the first disclosure of quinoline‐derived antibiotics inhibiting multidrug resistant Acinetobacter baumannii ATP synthase and expansion of the structure activity relationship profile of Pseudomonas aeruginosa ATP synthase inhibitors.
Katie T. Ward, Alexander P. L. Williams, Angelina L. Dennison, Lena Aamir, Darien L. Allen, Britza Chavez‐Arellano, Toni A. Marchlewski, Mars L. Zappia, Amanda L. Wolfe, P. Ryan Steed   +9 more
wiley   +1 more source

Development and evaluation of a catheter deliverable artificial aortic heart valve prosthesis and delivery system

, 2008
Thomas E. Claiborne
openalex   +2 more sources

A Phase 1C, Open Label, Single Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of DM199 Administered Intravenously with a Polyvinyl Chloride Bag in Adult Healthy Subjects and Adults Recently Taking Angiotensin‐Converting Enzyme Inhibitors

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This small phase 1C, open‐label, single ascending dose study evaluated the safety, tolerability, and pharmacokinetics (PKs) of DM199, a recombinant form of human tissue kallikrein‐1 (KLK1). A small sample size of both healthy subjects and hypertensive adults recently taking angiotensin‐converting enzyme inhibitors was studied. KLK1 has a known
Michael Giuffre, Annette D. Lista, Nick Paulson, Lorianne Masuoka   +3 more
wiley   +1 more source

Acute Effects and Pharmacokinetics of LSD after Paroxetine or Placebo Pre‐Administration in a Randomized, Double‐Blind, Cross‐Over Phase I Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Psychedelics, such as psilocybin and lysergic acid diethylamide (LSD), are being investigated for the treatment of depressive and anxiety disorders, for which concomitant treatment with selective serotonin reuptake inhibitors (SSRIs) is prevalent.
Anna M. Becker, Mélusine Humbert‐Droz, Lorenz Mueller, Alen Jelušić, Avram Tolev, Isabelle Straumann, Isidora Avedisian, Livio Erne, Jan Thomann, Dino Luethi, Edna Grünblatt, Henriette Meyer zu Schwabedissen, Matthias E. Liechti   +12 more
wiley   +1 more source

Reversing the “risk‐treatment paradox” of bleeding in patients undergoing percutaneous coronary intervention: Risk‐concordant use of bleeding avoidance strategies is associated with reduced bleeding and lower costs [PDF]

, 2018
Amin, Amit P, Bach, Richard, Caruso, Mary, Crimmins-Reda, Patricia, Kulkarni, Hemant, Kurz, Howard, Lasala, John M, Miller, Samantha, Pierce, Andrew, Rahn, Brandon, Singh, Jasvindar, Sorensen, Katrine, Zajarias, Alan   +12 more
core   +1 more source

Pharmacokinetics of Ethyl Glucuronide and Ethyl Sulfate and Pharmacodynamic Effects Following Intravenous and Oral Administration of Ethanol to Exercised Horses

Drug Testing and Analysis, EarlyView.
This study describes the pharmacokinetics of ethanol metabolites following intravenous and oral administration to horses. Based on rapid metabolism, ethyl glucuronide is the best candidate for monitoring of illicit administration to performance horses.
Heather K. Knych, Jeff Blea, Mary Scollay, Philip H. Kass, Daniel S. McKemie   +4 more
wiley   +1 more source

Retrieval Of A Fractured And Retained Percutaneous Coronary Angioplasty Catheter On Beating Perfused Heart

, 2009
Meenal Gulve, Nitin Gulve
openalex   +2 more sources

Administration Studies in Equine Antidoping Research: Designing Scientific Investigations to Effectively Direct Medication Control in Racehorses

Drug Testing and Analysis, EarlyView.
ABSTRACT Pharmacokinetics is the study of the movement of drug in the body and includes the processes of absorption, distribution, metabolism, and excretion. Pharmacodynamics is the pharmacologic effect of the drug on the body. The pharmacokinetics of a drug determines its pharmacologic effect. Pharmacokinetic studies describe drug concentrations while
Heather K. Knych
wiley   +1 more source