Results 1 to 10 of about 159,275 (311)

Development and Validation of the CHDSI Questionnaire: A New Tool for Measuring Disease-Specific Quality of Life in Children and Adolescents with Congenital Heart Defects [PDF]

open access: yesMedicina
Background and Objectives: Congenital heart defects (CHD) affect around 1% of the population, making them the most common congenital disease worldwide. Thanks to advances in treatment, over 90% of affected children are able to reach adulthood, shifting ...
Paul C. Helm   +3 more
doaj   +2 more sources

Sudden cardiac death in adults with congenital heart disease: Lessons to Learn from the ATROPOS registry

open access: yesInternational Journal of Cardiology Congenital Heart Disease, 2022
Sudden cardiac death (SCD) is one of the most frequent causes of death in adult patients with congenital heart disease (ACHD). Despite the rare frequency of its occurrence, the incident appears often when unexpected, and many affected patients had not ...
Alicia Jeanette Fischer   +5 more
doaj   +1 more source

Peak Oxygen Uptake on Cardiopulmonary Exercise Test Is a Predictor for Severe Arrhythmic Events during Three-Year Follow-Up in Patients with Complex Congenital Heart Disease

open access: yesJournal of Cardiovascular Development and Disease, 2022
Patients with congenital heart disease (CHD) are at increased risk for severe arrhythmia and sudden cardiac death (SCD). Although implantable cardioverter defibrillators (ICD) effectively prevent SCD, risk stratification for primary prophylaxis in ...
Felix von Sanden   +8 more
doaj   +1 more source

RNA expression profiles and regulatory networks in human right ventricular hypertrophy due to high pressure load

open access: yesiScience, 2021
Summary: Right ventricular hypertrophy (RVH) occurs in high pressure afterload, e.g., tetralogy of Fallot/pulmonary stenosis (TOF/PS). Such RVH is associated with alterations in energy metabolism, neurohormonal and epigenetic dysregulation (e.g ...
Philippe Chouvarine   +9 more
doaj   +1 more source

Umbilical catheter placement aided by coronary guidewires

open access: yesMolecular and Cellular Pediatrics, 2023
Catheterization of the umbilical vessels has proven to be an effective and relatively rapid method for gaining central vascular access in neonates.
Katarzyna Gendera   +5 more
doaj   +1 more source

Cardiac troponin T is necessary for normal development in the embryonic chick heart [PDF]

open access: yes, 2016
The heart is the first functioning organ to develop during embryogenesis. The formation of the heart is a tightly regulated and complex process, and alterations to its development can result in congenital heart defects.
England, Jennifer   +4 more
core   +4 more sources

Nationwide Registry‐Based Analysis of Infective Endocarditis Risk After Pulmonary Valve Replacement

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Infective endocarditis (IE) after pulmonary valve replacements in congenital heart disease is a significant concern. This study aimed to identify specific long‐term risk factors for IE after percutaneous pulmonary valve implantation or ...
Clara Stammnitz   +8 more
doaj   +1 more source

Microcephaly is associated with impaired educational development in children with congenital heart disease

open access: yesFrontiers in Cardiovascular Medicine, 2022
ObjectivesThis study aims to evaluate the school careers of patients with congenital heart disease (CHD) and microcephaly.MethodsAn exploratory online survey was conducted on patients from a previous study on somatic development in children with CHD in ...
Constanze Pfitzer   +15 more
doaj   +1 more source

Cardiac Muscle Training—A New Way of Recognizing and Supporting Recovery for LVAD Patients in the Pediatric Population

open access: yesLife, 2022
Patients with refractory heart failure due to chronic progressive cardiac myopathy (CM) may require mechanical circulatory support as a bridge to transplantation. A few patients can be weaned from support devices if recovery can be achieved.
Anca Racolta   +8 more
doaj   +1 more source

MEF2C regulates outflow tract alignment and transcriptional control of Tdgf1 [PDF]

open access: yes, 2016
Congenital heart defects are the most common birth defects in humans, and those that affect the proper alignment of the outflow tracts and septation of the ventricles are a highly significant cause of morbidity and mortality in infants.
Barnes, Ralston M.   +9 more
core   +1 more source

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