Results 31 to 40 of about 277,988 (265)

Development and Validation of the CHDSI Questionnaire: A New Tool for Measuring Disease-Specific Quality of Life in Children and Adolescents with Congenital Heart Defects

Medicina
Background and Objectives: Congenital heart defects (CHD) affect around 1% of the population, making them the most common congenital disease worldwide. Thanks to advances in treatment, over 90% of affected children are able to reach adulthood, shifting ...
Paul C. Helm, Ulrike M. M. Bauer, Peter Ewert, Julia Remmele   +3 more
doaj   +1 more source

Association Between Maternal Folic Acid Supplementation and Congenital Heart Defects in Offspring in Birth Cohorts From Denmark and Norway

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2019
Background Evidence linking individual‐level maternal folic acid supplementation to offspring risk of congenital heart defects is lacking. We investigated whether folic acid supplementation in early pregnancy reduces offspring risk of heart defects in 2 ...
N. Øyen, S. Olsen, S. Basit, E. Leirgul, M. Strøm, L. Carstensen, C. Granström, G. Tell, P. Magnus, S. Vollset, J. Wohlfahrt, M. Melbye   +11 more
semanticscholar   +1 more source

Folate supplementation for prevention of congenital heart defects and low birth weight: an update.

Cardiovascular Diagnosis and Therapy, 2019
Women planning a pregnancy and pregnant women in the first trimester are recommended to use folate-containing supplements in order to prevent neural tube defects.
R. Obeid, W. Holzgreve, K. Pietrzik
semanticscholar   +1 more source

Spatio-Temporal Distribution and Demographic Characteristics of Congenital Heart Defects in Guangdong, China, 2016–2020

Frontiers in Public Health, 2022
BackgroundCongenital heart defects are the most common type of birth defects and bring a heavy disease burden in China. Examining the temporal and spatial trends of congenital heart defects epidemics can give some elementary knowledge for succeeding ...
Huazhang Miao, Huazhang Miao, Huazhang Miao, Qinghui Zeng, Zengping Shi, Yi Xia, Lushaobo Shi, Dongxue Chen, Pi Guo, Yingxian Zhu, Dong Wang   +10 more
doaj   +1 more source

Interventional Partial Cavopulmonary Connection: Initial Clinical Experience With Acute Procedural up to Midterm Results

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Creation of a partial cavopulmonary anasthomosis in patients with isolated right‐sided heart failure or patients with cyanosis and intracardial right‐to‐left shunt and reduced blood flow in the pulmonary circulation may provide a significant ...
Katarzyna Gendera, Peter Ewert, Stanimir Georgiev, Andreas Eicken, Daniel Tanase, Kristina Borgmann, Paul Philipp Heinisch, Nicole Nagdyman, Julie Cleuziou, Dunja Renner, Pinar Bambul Heck   +10 more
doaj   +1 more source

It Is Not Carved in Stone—The Need for a Genetic Reevaluation of Variants in Pediatric Cardiomyopathies

Journal of Cardiovascular Development and Disease, 2022
(1) Background: In cardiomyopathies, identification of genetic variants is important for the correct diagnosis and impacts family cascade screening. A classification system was published by the American College of Medical Genetics and Genomics (ACMG) in ...
Dominik Sebastian Westphal, Kathrin Pollmann, Christoph Marschall, Annette Wacker-Gussmann, Renate Oberhoffer-Fritz, Karl-Ludwig Laugwitz, Peter Ewert, Cordula Maria Wolf   +7 more
doaj   +1 more source

Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing

Nature Genetics, 2016
Congenital heart defects (CHDs) have a neonatal incidence of 0.8–1% (refs. 1,2). Despite abundant examples of monogenic CHD in humans and mice, CHD has a low absolute sibling recurrence risk (∼2.7%), suggesting a considerable role for de novo mutations ...
A. Sifrim, M. Hitz, A. Wilsdon, J. Breckpot, S. A. Turki, B. Thienpont, J. McRae, Tomas W. Fitzgerald, T. Singh, G. Swaminathan, E. Prigmore, D. Rajan, H. Abdul-Khaliq, S. Banka, U. Bauer, J. Bentham, F. Berger, S. Bhattacharya, F. Bu'Lock, N. Canham, Irina Colgiu, C. Cosgrove, H. Cox, I. Daehnert, A. Daly, J. Danesh, A. Fryer, M. Gewillig, E. Hobson, K. Hoff, T. Homfray, A. Kahlert, A. Ketley, H. Kramer, K. Lachlan, Anne Katrin Lampe, J. Louw, Ashok Kumar Manickara, D. Manase, Karen P. McCarthy, K. Metcalfe, C. Moore, R. Newbury-Ecob, S. Omer, W. Ouwehand, Soo-Mi Park, M. Parker, T. Pickardt, Martin O Pollard, L. Robert, David J Roberts, J. Sambrook, Kerry Setchfield, B. Stiller, Chris Thornborough, O. Toka, H. Watkins, Denise Williams, M. Wright, S. Mital, P. Daubeney, B. Keavney, J. Goodship, R. Abu-Sulaiman, S. Klaassen, C. Wright, H. Firth, Jeffrey C. Barrett, K. Devriendt, David Fitzpatrick, J. Brook, M. Hurles   +71 more
semanticscholar   +1 more source

Mental Health Among Parents of Children With Critical Congenital Heart Defects: A Systematic Review

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2017
Background Parents of children with critical congenital heart defects (PCCHDs) may be at high risk for mental health morbidity; however, the literature is not well characterized.
Sarah E. Woolf-King, Alexandra Anger, Emily A. Arnold, S. Weiss, D. Teitel   +4 more
semanticscholar   +1 more source

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

Say NO to ROS: Their Roles in Embryonic Heart Development and Pathogenesis of Congenital Heart Defects in Maternal Diabetes

Antioxidants, 2019
Congenital heart defects (CHDs) are the most prevalent and serious birth defect, occurring in 1% of all live births. Pregestational maternal diabetes is a known risk factor for the development of CHDs, elevating the risk in the child by more than four ...
Anish Engineer, T. Saiyin, Elizabeth R. Greco, Q. Feng   +3 more
semanticscholar   +1 more source