Results 101 to 110 of about 3,197,237 (262)

Anomalous right pulmonary artery from the aorta [PDF]

, 2006
Anomalous origin of the right pulmonary artery is a rare form of congenital heart disease. It usually presents in early infancy with heart failure and rapid development of pulmonary hypertension. There are about 131 cases reported in the literature and
Mokhtar, S.A.I., Rasool, Aida Hanum Ghulam, Wong, Abdul Rahim   +2 more
core  

Double Cross‐Linked Hydrogel for Intra‐articular Injection as Modality for Macrophages Metabolic Reprogramming and Therapy of Rheumatoid Arthritis

Advanced Functional Materials, EarlyView.
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song, Valentin A. Milichko, Ziqiao Ding, Wen Li, Bei Kang, Yunsheng Dou, Sona Krizkova, Zbynek Heger, Nan Li   +8 more
wiley   +1 more source

Treating the patient not just the disease? : Delving deeper into the possible link between affective disorders and coronary heart disease through statistical analysis of a random sample of Maltese people [PDF]

, 2014
Background: Ischemic heart disease is the leading cause of death in Males in Malta and globally. Affective disorders are the commonest psychological problem.
Calleja, Neville, Debono, David
core  

High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles

Advanced Functional Materials, EarlyView.
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires, Ezra Gordon, Heikyung Suh, Darrell J. Irvine, Paula T. Hammond   +4 more
wiley   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

ON THE DIAGNOSIS OF DISEASES OF THE HEART. [PDF]

The Lancet
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openaire   +3 more sources

Laser‐Induced Graphene‐Assisted Patterning and Transfer of Silver Nanowires for Ultra‐Conformal Breathable Epidermal Electrodes in Long‐Term Electrophysiological Monitoring

Advanced Functional Materials, EarlyView.
This study presents a novel method using laser‐induced graphene (LIG) to enable high‐yield transfer of silver nanowire (AgNW) networks onto ultra‐low modulus, breathable silicone substrates. This approach creates ultra‐conformal epidermal electrodes (≈50 µm) for long‐term, high‐fidelity electrophysiological monitoring, even in challenging conditions ...
Jiuqiang Li, Senhao Zhang, Jun Zhong, Benkun Bao, Kai Guo, Yingying Zhang, Kerong Yang, Yao Tong, Donghai Qiu, Hongbo Yang, Huanyu Cheng   +10 more
wiley   +1 more source

A Universal Biomimetic Approach for Making Artificial Antigen‐Presenting Cells for T Cell Activation

Advanced Functional Materials, EarlyView.
This study shows a biomimetic silica microcapsule (SMC) fabrication method under mild conditions for making artificial antigen‐presenting cells (aAPCs). Inspired by marine biomineralization, peptide‐mediated biosilicification enables silica shell formation on emulsion templates. The resulting SMCs possess a core–shell structure, controlled fluorescence
Fei Hou, Supun Ranaweera, Xiangke Li, Ruirui Qiao, Yue Hui, Chun‐Xia Zhao   +5 more
wiley   +1 more source

Microbubble‐Controlled Delivery of Biofilm‐Targeting Nanoparticles to Treat MRSA Infection

Advanced Functional Materials, EarlyView.
Here, an effective strategy using microbubble (MB)‐controlled delivery of biofilm‐targeting nanoparticles (BTNs) for removal and therapy of methicillin‐resistant Staphylococcus aureus (MRSA) biofilm infections is introduced. In vivo delivery of MB with BTN is demonstrated to silence key bacterial genes involved in biofilm formation (icaA), bacterial ...
Ju Yeon Chung, Yujin Ahn, Joo Hun Lee, Seungju Yang, Seung Cheol Lee, Hyunjoon Kong, Hyun Jung Chung   +6 more
wiley   +1 more source

Pericyte‐Assisted Vascular Lumen Organization in a Novel Dynamic Human Blood‐Brain Barrier‐on‐Chip Model

Advanced Healthcare Materials, EarlyView.
Organ‐on‐Chip (OoC) technology enables the precise modeling of the blood‐brain barrier (BBB). This study presents a microfluidic device that mimics brain microvessels, integrating co‐culture with pericytes and astrocytes under pulsatile flow. Results show that perivascular cells modulate endothelial morphology, promoting lumen formation and barrier ...
Vita Guarino, Elisabetta Perrone, Elisa De Luca, Alberto Rainer, Maura Cesaria, Alessandra Zizzari, Monica Bianco, Giuseppe Gigli, Lorenzo Moroni, Valentina Arima   +9 more
wiley   +1 more source